Typical Testing Data/Standard Curve (for reference only)
(Human TNFRSF19/TROY PicoKine ELISA Kit standard curve )
Human TNFRSF19/TROY ELISA Kit | TNFRSF19 elisa kit
Human TNFRSF19/TROY PicoKine ELISA Kit
Gene Names
TNFRSF19; TAJ; TROY; TRADE; TAJ-alpha
Reactivity
Human
Synonyms
TNFRSF19/TROY; Human TNFRSF19/TROY PicoKine ELISA Kit; TAJ; TROY; TRADE; TAJ-alpha; TAJ alpha; TNFRSF 19; TNFRSF19; UNQ1888/PRO4333; Q9NS68; Tumor necrosis factor receptor superfamily member 19; TNF receptor superfamily member 19; TNFRSF19 elisa kit
Reactivity
Human
Specificity
Natural and recombinant Human TNFRSF19/TROY
Sequence Length
417
Samples
Cell culture supernates, cell lysates, tissue homogenates, serum and plasma (heparin, EDTA)
Assay Type
Quantitative Sandwich
Detection Range
62.5pg/ml-4000pg/ml
Sensitivity
<12pg/ml
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles.
Typical Testing Data/Standard Curve (for reference only)
(Human TNFRSF19/TROY PicoKine ELISA Kit standard curve )
Typical Testing Data/Standard Curve (for reference only)
(Human TNFRSF19/TROY PicoKine ELISA Kit standard curve )
Related Product Information for TNFRSF19 elisa kit
Principle of the Assay: The Human TNFRSF19/TROY ELISA Kit was based on standard sandwich enzyme-linked immunesorbent assay technology. A monoclonal antibody from mouse specific for TNFRSF19/TROY has been precoated onto 96-well plates. Standards(Expression system for standard: NSO, Immunogen sequence: E30-L170) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for TNFRSF19/TROY is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the Human TNFRSF19/TROY amount of sample captured in plate.
Background: Tumor necrosis factor receptor superfamily, member 19, also known as TNFRSF19 and TROY, is a human gene. It is mapped to 13q12.11-q12.3. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Background: Tumor necrosis factor receptor superfamily, member 19, also known as TNFRSF19 and TROY, is a human gene. It is mapped to 13q12.11-q12.3. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,542 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 19 isoform 2
NCBI Official Synonym Full Names
TNF receptor superfamily member 19
NCBI Official Symbol
TNFRSF19
NCBI Official Synonym Symbols
TAJ; TROY; TRADE; TAJ-alpha
NCBI Protein Information
tumor necrosis factor receptor superfamily member 19
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 19
Protein Family
UniProt Gene Name
TNFRSF19
UniProt Synonym Gene Names
TAJ; TROY
NCBI Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
TNFRSF19: Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q12.12
Cellular Component: plasma membrane
Molecular Function: receptor activity
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; tissue development
Research Articles on TNFRSF19
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Product Notes
The Human TNFRSF19 tnfrsf19 (Catalog #AAA178768) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA178768 ELISA Kit recognizes Human TNFRSF19. It is sometimes possible for the material contained within the vial of "TNFRSF19/TROY, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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