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Flow Cytometry (FC/FACS) (Flow Cytometry of XB-2 cells using MBS620236 (filled histogram) or isotype control (open histogram).)

Goat anti-Mouse TROP-2 Polyclonal Antibody | anti-TACSTD2 antibody

TROP-2 (Tumor-associated Calcium Signal Transducer 2 and Lymphocyte Antigen 97, TACSTD2), GA733 Tumor Associated Antigen and Epithelial Glycoprotein-1, EGP-1) (APC)

Gene Names
TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Purity
Affinity Purified
Purified by immunoaffinity chromatography.
Synonyms
TROP-2; Polyclonal Antibody; TROP-2 (Tumor-associated Calcium Signal Transducer 2 and Lymphocyte Antigen 97; TACSTD2); GA733 Tumor Associated Antigen and Epithelial Glycoprotein-1; EGP-1) (APC); Anti -TROP-2 (Tumor-associated Calcium Signal Transducer 2 and Lymphocyte Antigen 97; anti-TACSTD2 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse cell surface glycoprotein TROP-2.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with APC.
Applicable Applications for anti-TACSTD2 antibody
Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Flow Cytometry.
Dilution: Flow Cytometry: 10ul per 1-2.5x10e5 cells
Immunogen
NS0-derived, recombinant mouse cell surface glycoprotein TROP-2, extracellular domain (Ser 82-Thr268, Accession #Q8BGV3)
Preparation and Storage
May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Freezing allophycocyanin conjugates will result in a substantial loss of activity. Allophycocyanin conjugates are sensitive to light.

Flow Cytometry (FC/FACS)

(Flow Cytometry of XB-2 cells using MBS620236 (filled histogram) or isotype control (open histogram).)

Flow Cytometry (FC/FACS) (Flow Cytometry of XB-2 cells using MBS620236 (filled histogram) or isotype control (open histogram).)
Related Product Information for anti-TACSTD2 antibody
TROP-2, also named tumor-associated calcium signal transducer 2 (TACSTD2), GA733 tumor associated antigen and epithelial glycoprotein-1 (EGP-1), is a type I transmembrane protein highly expressed in carcinomas.
Product Categories/Family for anti-TACSTD2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,709 Da
NCBI Official Full Name
tumor-associated calcium signal transducer 2
NCBI Official Synonym Full Names
tumor-associated calcium signal transducer 2
NCBI Official Symbol
TACSTD2
NCBI Official Synonym Symbols
EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
NCBI Protein Information
tumor-associated calcium signal transducer 2; epithelial glycoprotein-1; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; pancreatic carcinoma marker protein GA7331; pancreatic carcinoma marker protein GA733-1; gastrointestinal tumor-associated antigen GA7331; membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; 40kD glycoprotein, identified by monoclonal antibody GA733
UniProt Protein Name
Tumor-associated calcium signal transducer 2
UniProt Gene Name
TACSTD2
UniProt Synonym Gene Names
GA733-1; M1S1; TROP2
UniProt Entry Name
TACD2_HUMAN

NCBI Description

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]

Uniprot Description

TACSTD2: May function as a growth factor receptor. Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD); also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment. Belongs to the EPCAM family.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p32

Cellular Component: extracellular space; membrane; integral to plasma membrane; basal plasma membrane; cytosol; nucleus; lateral plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: cell proliferation; cell surface receptor linked signal transduction; negative regulation of stress fiber formation; visual perception; regulation of epithelial cell proliferation

Disease: Corneal Dystrophy, Gelatinous Drop-like

Research Articles on TACSTD2

Similar Products

Product Notes

The TACSTD2 tacstd2 (Catalog #AAA620236) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The TROP-2 (Tumor-associated Calcium Signal Transducer 2 and Lymphocyte Antigen 97, TACSTD2), GA733 Tumor Associated Antigen and Epithelial Glycoprotein-1, EGP-1) (APC) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TROP-2 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Suitable for use in Flow Cytometry. Dilution: Flow Cytometry: 10ul per 1-2.5x10e5 cells. Researchers should empirically determine the suitability of the TACSTD2 tacstd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TROP-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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