Rabbit anti-Human TRIM7 Polyclonal Antibody | anti-TRIM7 antibody

TRIM7, NT (TRIM7, GNIP, RNF90, Tripartite motif-containing protein 7, Glycogenin-interacting protein, RING finger protein 90) (AP)

Cat. Num. AAA6358583

• Gene Names: TRIM7; GNIP; RNF90
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TRIM7; Polyclonal Antibody; NT (TRIM7; GNIP; RNF90; Tripartite motif-containing protein 7; Glycogenin-interacting protein; RING finger protein 90) (AP); RING finger protein 90; anti-TRIM7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-TRIM7 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:10-50; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: TRIM7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human TRIM7.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Immunohistochemistry (IHC)

(TRIM7 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIM7 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Western Blot (WB)

(TRIM7 Antibody (N-term) western blot analysis in NCI-H292,HepG2 cell line lysates (35ug/lane).This demonstrates the TRIM7 antibody detected the TRIM7 protein (arrow).)

Related Product Information for anti-TRIM7 antibody

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to both the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis. Multiple transcript variants have been found for this gene, and some of them encode the same isoform. [provided by RefSeq].

Product Categories/Family for anti-TRIM7 antibody

Antibodies; Transcription Factors; TRIM (Tripartite Motif)

References

Zhai, L., et al. Arch. Biochem. Biophys. 421(2):236-242(2004). Skurat, A.V., et al. J. Biol. Chem. 277(22):19331-19338(2002). Reymond, A., et al. EMBO J. 20(9):2140-2151(2001).

NCBI and Uniprot Product Information

• NCBI GI #: 16076875
• NCBI GeneID: 81786
• NCBI Accession #: NP_203128.1
• NCBI GenBank Nucleotide #: NM_033342.3
• UniProt Accession #: Q9C029; Q969F5; Q96F67; Q96J89; Q96J90; A2RUE4; D3DWR7
• Molecular Weight: 23,700 Da
• NCBI Official Full Name: tripartite motif-containing protein 7 isoform 4
• NCBI Official Synonym Full Names: tripartite motif containing 7
• NCBI Official Symbol: TRIM7
• NCBI Official Synonym Symbols: GNIP; RNF90
• NCBI Protein Information: tripartite motif-containing protein 7; RING finger protein 90; glycogenin-interacting protein; tripartite motif protein TRIM7
• UniProt Protein Name: Tripartite motif-containing protein 7
• Protein Family: Tripartite motif-containing protein
• UniProt Gene Name: TRIM7
• UniProt Synonym Gene Names: GNIP; RNF90
• UniProt Entry Name: TRIM7_HUMAN

NCBI Description

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to both the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

TRIM7: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to both the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis. Multiple transcript variants have been found for this gene, and some of them encode the same isoform. [provided by RefSeq, Jul 2008]

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: cytoplasm; nucleus

Molecular Function: zinc ion binding