Western Blot (WB)
(WB Suggested Anti-TRIM38 Antibody Titration: 5.0ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate)
Rabbit anti-Human, Pig TRIM38 Polyclonal Antibody | anti-TRIM38 antibody
TRIM38 antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-TRIM38 Antibody Titration: 5.0ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate)
Western Blot (WB)
(WB Suggested Anti-TRIM38 Antibody Titration: 5.0ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate)
Target Description: TRIM38 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012]
Uniprot Description
TRIM38: E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling. {ECO:0000269|PubMed:23056470}
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: cytosol
Molecular Function: signal transducer activity; zinc ion binding; ligase activity
Biological Process: proteasomal ubiquitin-dependent protein catabolic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of viral genome replication; positive regulation of virion penetration into host cell; cytokine and chemokine mediated signaling pathway; positive regulation of transcription factor activity; regulation of interferon-beta production; negative regulation of defense response to virus; activation of NF-kappaB transcription factor
Research Articles on TRIM38
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Product Notes
The TRIM38 trim38 (Catalog #AAA3204275) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRIM38 antibody - N-terminal region reacts with Human, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's TRIM38 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the TRIM38 trim38 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: MASTTSTKKM MEEATCSICL SLMTNPVSIN CGHSYCHLCI TDFFKNPSQK. It is sometimes possible for the material contained within the vial of "TRIM38, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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