Western Blot (WB)
(TREX1 rabbit polyclonal antibody. Western Blot analysis of TREX1 expression in mouse spleen.)
Rabbit anti-Human, Mouse TREX1 Polyclonal Antibody | anti-TREX1 antibody
TREX1 (Three Prime Repair Exonuclease 1, 3'-5' Exonuclease TREX1, AGS1, CRV, DNase III, DRN3, HERNS) (FITC)
Gene Names
TREX1; CRV; AGS1; DRN3; HERNS
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
TREX1; Polyclonal Antibody; TREX1 (Three Prime Repair Exonuclease 1; 3'-5' Exonuclease TREX1; AGS1; CRV; DNase III; DRN3; HERNS) (FITC); EC=3.1.11.2; anti-TREX1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human TREX1. Species Crossreactivity: mouse.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-TREX1 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human TREX1, aa1-369 (NP_057465.1).
Immunogen Sequence
MGPGARRQGRIVQGRPEMCFCPPPTPLPPLRILTLGTHTPTPCSSPGSAAGTYPTMGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE
Conjugate
FITC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(TREX1 rabbit polyclonal antibody. Western Blot analysis of TREX1 expression in mouse spleen.)
Western Blot (WB)
(TREX1 rabbit polyclonal antibody. Western Blot analysis of TREX1 expression in mouse spleen.)
Western Blot (WB)
(Western Blot analysis of TREX1 expression in transfected 293T cell line by TREX1 polyclonal antibody. Lane 1: TREX1 transfected lysate (38.9kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of TREX1 expression in transfected 293T cell line by TREX1 polyclonal antibody. Lane 1: TREX1 transfected lysate (38.9kD). Lane 2: Non-transfected lysate.)
Product Categories/Family for anti-TREX1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Synonym Full Names
three prime repair exonuclease 1
NCBI Official Symbol
TREX1
NCBI Official Synonym Symbols
CRV; AGS1; DRN3; HERNS
NCBI Protein Information
three-prime repair exonuclease 1
Protein Family
NCBI Description
This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
Research Articles on TREX1
1. Familial cryofibrinogenemia without lupus should be added to the spectrum of TREX1-related disease.
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Product Notes
The TREX1 (Catalog #AAA6397130) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TREX1 (Three Prime Repair Exonuclease 1, 3'-5' Exonuclease TREX1, AGS1, CRV, DNase III, DRN3, HERNS) (FITC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TREX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TREX1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TREX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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