Western Blot (WB)
(All lanes: Transcription factor SOX-2 antibody at 2ug/ml+mouse kidney tissue)
Rabbit anti-Human Transcription factor SOX-2 Polyclonal Antibody | anti-SOX2 antibody
Transcription factor SOX-2 Polyclonal Antibody
Western Blot (WB)
(All lanes: Transcription factor SOX-2 antibody at 2ug/ml+mouse kidney tissue)
Western Blot (WB)
(All lanes: Transcription factor SOX-2 antibody at 2ug/ml+mouse kidney tissue)
NCBI and Uniprot Product Information
Uniprot Description
SOX2: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Interacts with ZSCAN10. Interacts with SOX3 and FGFR1.
Protein type: Cell development/differentiation; DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 3q26.3-q27
Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus; transcription factor complex
Molecular Function: DNA binding; miRNA binding; protein binding; sequence-specific DNA binding; transcription factor activity
Biological Process: cell cycle arrest; endodermal cell fate specification; eye development; forebrain development; inner ear development; negative regulation of epithelial cell proliferation; negative regulation of neuron differentiation; negative regulation of transcription from RNA polymerase II promoter; osteoblast differentiation; pituitary gland development; positive regulation of MAPKKK cascade; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of caspase activity; regulation of gene expression; regulation of transcription, DNA-dependent; response to wounding; somatic stem cell maintenance
Disease: Microphthalmia, Syndromic 3; Tracheoesophageal Fistula With Or Without Esophageal Atresia
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Product Notes
The SOX2 sox2 (Catalog #AAA9416394) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Transcription factor SOX-2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Transcription factor SOX-2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500 - 1:1000. Researchers should empirically determine the suitability of the SOX2 sox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transcription factor SOX-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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