Rabbit anti-Human TPRA1 Polyclonal Antibody | anti-TPRA1 antibody

TPRA1 Polyclonal Antibody

Cat. Num. AAA3007091

• Reactivity: Human
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: TPRA1; Polyclonal Antibody; TPRA1 Polyclonal Antibody; Transmembrane protein adipocyte-associated 1; Integral membrane protein GPR175; Transmembrane protein 227; GPR175; TMEM227; PP6566; anti-TPRA1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: TPRA1 polyclonal antibody detects endogenous levels of TPRA1 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 373

• Applicable Applications for anti-TPRA1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to residues in Human TPRA1.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of TPRA1 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysateLane2:MCF-7 whole cell lysate)

Related Product Information for anti-TPRA1 antibody

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR175 (G protein-coupled receptor 175), also known as TPRA40 or PP6566, is a 373 amino acid multi-pass membrane protein that is ubiquitously expressed and functions as a G-protein coupled receptor. The gene encoding GPR175 maps to human chromosome 3 and is expressed as multiple alternatively spliced isoforms.

NCBI and Uniprot Product Information

• NCBI GI #: 209862909
• NCBI Accession #: NP_001129525.1
• NCBI GenBank Nucleotide #: NP_001129525.1
• UniProt Accession #: Q86W33
• Molecular Weight: ~ 41kDa
• NCBI Official Full Name: transmembrane protein adipocyte-associated 1 isoform 1
• UniProt Protein Name: Transmembrane protein adipocyte-associated 1
• Protein Family: Transmembrane protein adipocyte-associated
• UniProt Gene Name: TPRA1
• UniProt Synonym Gene Names: GPR175; TMEM227
• UniProt Entry Name: TPRA1_HUMAN

Uniprot Description

GPR175: Belongs to the UPF0359 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q21.2

Cellular Component: integral to membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; lipid metabolic process; aging