Immunohistochemistry (IHC)
(Immunohistochemical staining of TP53INP2 in formalin-fixed, paraffin-embedded human testis using usingMBS623501. Detection: HRP-conjugated secondary antibody/DAB staining.)
Rabbit anti-Human, Mouse TP53INP2 Polyclonal Antibody | anti-TP53INP2 antibody
TP53INP2, CT (Tumor Protein p53-inducible Nuclear Protein 2, p53-inducible Protein U, PIG-U, PINH, C20orf110, DOR) (Azide free) (HRP)
Gene Names
TP53INP2; DOR; PINH; FLJ21759; FLJ23500; C20orf110; dJ1181N3.1; DKFZp434B2411; DKFZp434O0827
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified by Immunoaffinity chromatography.
Synonyms
TP53INP2; Polyclonal Antibody; CT (Tumor Protein p53-inducible Nuclear Protein 2; p53-inducible Protein U; PIG-U; PINH; C20orf110; DOR) (Azide free) (HRP); anti-TP53INP2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human TP53INP2. Species Crossreactivity: mouse.
Purity/Purification
Purified by Immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Applicable Applications for anti-TP53INP2 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes
IHC: 1:50-1:100
ELISA: 1:1,000
WB: 1:100-1:500
Applications are based on unconjugated antibody.
ELISA: 1:1,000
WB: 1:100-1:500
Applications are based on unconjugated antibody.
Immunogen
KLH conjugated synthetic peptide between a portion within aa 179~208 in the C-terminal region of human TP53INP2
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunohistochemistry (IHC)
(Immunohistochemical staining of TP53INP2 in formalin-fixed, paraffin-embedded human testis using usingMBS623501. Detection: HRP-conjugated secondary antibody/DAB staining.)
Immunohistochemistry (IHC)
(Immunohistochemical staining of TP53INP2 in formalin-fixed, paraffin-embedded human testis using usingMBS623501. Detection: HRP-conjugated secondary antibody/DAB staining.)
Flow Cytometry (FC/FACS)
(Flow cytometry analysis of HeLa cells (bottom histogram) compared to negative control cells (top histogram). FITC-conjugated goat anti-rabbit secondary antibody was used for detection.)
Flow Cytometry (FC/FACS)
(Flow cytometry analysis of HeLa cells (bottom histogram) compared to negative control cells (top histogram). FITC-conjugated goat anti-rabbit secondary antibody was used for detection.)
Product Categories/Family for anti-TP53INP2 antibody
References
1. Bennetts, J.S., et.al., Dev. Dyn. 236 (3), 843-852 (2007). 2. Jonathan Nowak, Cendrine Archange, et.al., Molecular Biology of the Cell Vol. 20, 870-881, February 1, 2009. 3. Bernhard G. Baumgartner, et.al., Plos one: November 2007 Issue 11 e1183.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,980 Da
NCBI Official Full Name
tumor protein p53-inducible nuclear protein 2
NCBI Official Synonym Full Names
tumor protein p53 inducible nuclear protein 2
NCBI Official Symbol
TP53INP2
NCBI Official Synonym Symbols
DOR; PINH; FLJ21759; FLJ23500; C20orf110; dJ1181N3.1; DKFZp434B2411; DKFZp434O0827
NCBI Protein Information
tumor protein p53-inducible nuclear protein 2; PIG-U; OTTHUMP00000030701; OTTHUMP00000030703; p53-inducible protein U; diabetes and obesity regulated
UniProt Protein Name
Tumor protein p53-inducible nuclear protein 2
Protein Family
UniProt Gene Name
TP53INP2
UniProt Synonym Gene Names
C20orf110; PINH
UniProt Entry Name
T53I2_HUMAN
Uniprot Description
TP53INP2: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.
Chromosomal Location of Human Ortholog: 20q11.22
Cellular Component: PML body; autophagic vacuole; cytoplasmic vesicle; cytosol; nucleus
Molecular Function: protein binding
Biological Process: osteoblast differentiation; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of autophagy; autophagic vacuole formation
Research Articles on TP53INP2
Similar Products
Product Notes
The TP53INP2 tp53inp2 (Catalog #AAA6502689) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TP53INP2, CT (Tumor Protein p53-inducible Nuclear Protein 2, p53-inducible Protein U, PIG-U, PINH, C20orf110, DOR) (Azide free) (HRP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TP53INP2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:50-1:100 ELISA: 1:1,000 WB: 1:100-1:500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TP53INP2 tp53inp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TP53INP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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