Rabbit anti-Human TOR2A Polyclonal Antibody | anti-TOR2A antibody

TOR2A, ID (TOR2A, TORP1, Torsin-2A, Torsin family 2 member A, Torsin-related protein 1) (Biotin)

Cat. Num. AAA6357441

• Gene Names: TOR2A; TORP1
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TOR2A; Polyclonal Antibody; ID (TOR2A; TORP1; Torsin-2A; Torsin family 2 member A; Torsin-related protein 1) (Biotin); Torsin-related protein 1; anti-TOR2A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-TOR2A antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:10-50; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: TOR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-229 amino acids from the Central region of human TOR2A.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TOR2A Antibody (Center) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the TOR2A antibody detected the TOR2A protein (arrow).)

Immunohistochemistry (IHC)

(TOR2A Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TOR2A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Product Categories/Family for anti-TOR2A antibody

Antibodies; Lipoproteins

References

O'Farrell, C.A., et al. Neuroscience 164(3):1127-1137(2009). Sato, K., et al. Peptides 29(12):2203-2207(2008). Watanabe, T., et al. Hypertens. Res. 31(3):463-468(2008). Wang, Z., et al. Eur. J. Pharmacol. 539(3):145-150(2006). Humphray, S.J., et al. Nature 429(6990):369-374(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 197313700
• NCBI GeneID: 27433
• NCBI Accession #: NP_001127902.1; NP_569726.2
• NCBI GenBank Nucleotide #: NM_001134430.2
• UniProt Accession #: Q5JU69; Q8N2E6
• Molecular Weight: 35,714 Da
• NCBI Official Full Name: prosalusin isoform c
• NCBI Official Synonym Full Names: torsin family 2 member A
• NCBI Official Symbol: TOR2A
• NCBI Official Synonym Symbols: TORP1
• NCBI Protein Information: prosalusin
• UniProt Protein Name: Torsin-2A
• Protein Family: Torsin
• UniProt Gene Name: TOR2A
• UniProt Synonym Gene Names: TORP1

NCBI Description

This gene encodes a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis. The antimicrobial peptide salusin-beta has antibacterial activity. [provided by RefSeq, Nov 2014]