Western Blot (WB)
(Western blot analysis of TNFAIP2 in K562 cell lysate with TNFAIP2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human TNFAIP2 Polyclonal Antibody | anti-TNFAIP2 antibody
TNFAIP2 Antibody
Gene Names
TNFAIP2; B94; EXOC3L3
Reactivity
Human
Applications
ELISA, Western Blot, Immunofluorescence
Purity
TNFAIP2 Antibody is affinity chromatography purified via peptide column.
Synonyms
TNFAIP2; Polyclonal Antibody; TNFAIP2 Antibody; B94; EXOC3L3; Tumor necrosis factor alpha-induced protein 2; Primary response gene B94 protein; TNF alpha-induced protein 2; tumor necrosis factor; alpha-induced protein 2; anti-TNFAIP2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
At least two isoforms of TNFAIP2 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with TNFAIP3.
Purity/Purification
TNFAIP2 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
654
Applicable Applications for anti-TNFAIP2 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes
TNFAIP2 antibody can be used for detection of TNFAIP2 by Western blot at 1 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
TNFAIP2 antibody was raised against a 19 amino acid synthetic peptide near the center of human TNFAIP2.
Buffer
TNFAIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
TNFAIP2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of TNFAIP2 in K562 cell lysate with TNFAIP2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of TNFAIP2 in K562 cell lysate with TNFAIP2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunofluorescence (IF)
(Immunofluorescence of TNFAIP2 in K562 cells with TNFAIP2 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of TNFAIP2 in K562 cells with TNFAIP2 antibody at 20 μg/mL.)
Related Product Information for anti-TNFAIP2 antibody
TNFAIP2 Antibody: TNFAIP2, also known as B94, is a TNF-a-regulated gene that is expressed in endothelial cells, peripheral blood cells, and mature sperm. Recently, elevated TNFAIP2 expression was observed in nasopharyngeal carcinoma, and high expression of TNFAIP2 was significantly correlated with higher levels of cell migration, invasion and metastasis, suggesting that TNFAIP2 may serve as a useful prognostic indicator for nasopharyngeal carcinoma. TNFAIP2 has also been implicated as part of the viral-sensing circuit of the innate immune response.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
72 kDa
NCBI Official Full Name
tumor necrosis factor alpha-induced protein 2
NCBI Official Synonym Full Names
tumor necrosis factor, alpha-induced protein 2
NCBI Official Symbol
TNFAIP2
NCBI Official Synonym Symbols
B94; EXOC3L3
NCBI Protein Information
tumor necrosis factor alpha-induced protein 2; TNF alpha-induced protein 2; primary response gene B94 protein; exocyst complex component 3-like 3
UniProt Protein Name
Tumor necrosis factor alpha-induced protein 2
Protein Family
UniProt Gene Name
TNFAIP2
UniProt Synonym Gene Names
TNF alpha-induced protein 2
UniProt Entry Name
TNAP2_HUMAN
NCBI Description
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008]
Uniprot Description
TNFAIP2: May play a role as a mediator of inflammation and angiogenesis. Belongs to the SEC6 family.
Chromosomal Location of Human Ortholog: 14q32
Cellular Component: extracellular space; exocyst
Molecular Function: SNARE binding
Biological Process: exocytosis; angiogenesis; exocyst localization; cell differentiation
Research Articles on TNFAIP2
Similar Products
Product Notes
The TNFAIP2 tnfaip2 (Catalog #AAA153553) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TNFAIP2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TNFAIP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). TNFAIP2 antibody can be used for detection of TNFAIP2 by Western blot at 1 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the TNFAIP2 tnfaip2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNFAIP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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