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Western Blot (WB) (Western blot analysis of TMEM147 in Daudi cell lysate with TMEM147 antibody at (A) 1 and (B) 2 ug/mL.)

Rabbit TMEM147 Polyclonal Antibody | anti-TMEM147 antibody

TMEM147 Antibody

Gene Names
TMEM147; NIFIE14
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
TMEM147; Polyclonal Antibody; TMEM147 Antibody; Transmembrane protein 147; MGC1936; NIFIE14; anti-TMEM147 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
224
Applicable Applications for anti-TMEM147 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 13 amino acid peptide near the center of human TMEM147.
Target Name
TMEM147
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of TMEM147 in Daudi cell lysate with TMEM147 antibody at (A) 1 and (B) 2 ug/mL.)

Western Blot (WB) (Western blot analysis of TMEM147 in Daudi cell lysate with TMEM147 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-TMEM147 antibody
TMEM147 is a recently identified protein that associates with Nicalin and NOMO, forming a complex that is thought to be similar to the gamma-secretase complex. TMEM147 localizes to the endoplasmic reticulum (ER), and in zebrafish, is expressed during early development. TMEM147 also interacts with the M3 muscarinic receptor (M3R) in the ER and is thought to negatively its expression and function.
Product Categories/Family for anti-TMEM147 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,543 Da
NCBI Official Full Name
transmembrane protein 147 isoform 1
NCBI Official Synonym Full Names
transmembrane protein 147
NCBI Official Symbol
TMEM147
NCBI Official Synonym Symbols
NIFIE14
NCBI Protein Information
transmembrane protein 147
UniProt Protein Name
Transmembrane protein 147
Protein Family
UniProt Gene Name
TMEM147
UniProt Entry Name
TM147_HUMAN

Uniprot Description

TMEM147: Forms a complex with NCLN and NOMO2, resulting in a stabilization of the 3 proteins, which are otherwise quickly degraded by the proteasome. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, probably also interacts with NOMO1 and NOMO3.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Research Articles on TMEM147

Similar Products

Product Notes

The TMEM147 tmem147 (Catalog #AAA9403361) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEM147 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TMEM147 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the TMEM147 tmem147 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEM147, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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