Rabbit anti-Human, Mouse TMEM107 Polyclonal Antibody | anti-TMEM107 antibody
TMEM107 Antibody
Gene Names
TMEM107; GRVS638; PRO1268
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
TMEM107; Polyclonal Antibody; TMEM107 Antibody; DC20; GRVS638; MGC10744; PRO1268; TM107_HUMAN; Tmem107; Transmembrane protein 107; UNQ638/PRO1268; anti-TMEM107 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
TMEM107 Antibody detects endogenous levels of TMEM107.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-TMEM107 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human TMEM107.
Conjugation
Unconjugated
Subunit Structure
Part of the tectonic-like complex (also named B9 complex). Interacts with TMEM237, TMEM231, MKS1 and TMEM216.
Function
Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types (By similarity). During ciliogenesis regulates the ciliary transition zone localization of some MKS complex proteins.
Note
Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-TMEM107 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 16 kDa
Observed: 19kDa
Observed: 19kDa
NCBI Official Full Name
transmembrane protein 107 isoform 1
NCBI Official Synonym Full Names
transmembrane protein 107
NCBI Official Symbol
TMEM107
NCBI Official Synonym Symbols
GRVS638; PRO1268
NCBI Protein Information
transmembrane protein 107
UniProt Protein Name
Transmembrane protein 107
Protein Family
UniProt Gene Name
TMEM107
UniProt Entry Name
TM107_HUMAN
Uniprot Description
TMEM107: Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: integral to membrane
Biological Process: neural tube patterning; cilium biogenesis; embryonic digit morphogenesis
Research Articles on TMEM107
Similar Products
Product Notes
The TMEM107 tmem107 (Catalog #AAA9630687) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEM107 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TMEM107 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the TMEM107 tmem107 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEM107, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
