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Immunofluorescence (IF) (Immunofluorescent analysis of MCF-7 cells using MBS1495646 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Rabbit anti-Human TMEM100 Polyclonal Antibody | anti-TMEM100 antibody

TMEM100 Antibody

Reactivity
Human
Applications
ELISA, Immunofluorescence
Purity
>95%, Protein G Purified
Synonyms
TMEM100; Polyclonal Antibody; TMEM100 Antibody; Transmembrane protein 100; anti-TMEM100 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
134
Applicable Applications for anti-TMEM100 antibody
ELISA (EIA), Immunofluorescence (IF)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Transmembrane protein 100 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-165724 / sc-165726 / sc-165727
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunofluorescence (IF)

(Immunofluorescent analysis of MCF-7 cells using MBS1495646 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunofluorescence (IF) (Immunofluorescent analysis of MCF-7 cells using MBS1495646 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-TMEM100 antibody
Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,386 Da
NCBI Official Full Name
transmembrane protein 100
NCBI Official Synonym Full Names
transmembrane protein 100
NCBI Official Symbol
TMEM100
NCBI Protein Information
transmembrane protein 100
UniProt Protein Name
Transmembrane protein 100
Protein Family
UniProt Gene Name
TMEM100
UniProt Entry Name
TM100_HUMAN

Uniprot Description

TMEM100: Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Up-regulated by GDF2/BMP9 and BMP10 (at protein level)

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: endoplasmic reticulum; integral to membrane; perikaryon; perinuclear region of cytoplasm; plasma membrane

Molecular Function: protein binding

Biological Process: angiogenesis; BMP signaling pathway; in utero embryonic development; Notch signaling pathway; positive regulation of endothelial cell differentiation; protein kinase B signaling cascade; regulation of calcium-mediated signaling; regulation of sensory perception of pain; vasculogenesis

Research Articles on TMEM100

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Product Notes

The TMEM100 tmem100 (Catalog #AAA1495646) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEM100 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TMEM100 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF). Researchers should empirically determine the suitability of the TMEM100 tmem100 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEM100, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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