Western Blot (WB)
(Western blot analysis of TM2D1 using K562 whole cell lysates)
Rabbit TM2D1 Polyclonal Antibody | anti-TM2D1 antibody
TM2D1 Antibody
Gene Names
TM2D1; BBP
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
TM2D1; Polyclonal Antibody; TM2D1 Antibody; BBP; Beta amyloid binding protein; hBBP; TM2 domain containing 1; TM2 domain containing protein 1; anti-TM2D1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
TM2D1 antibody detects endogenous levels of total TM2D1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
207
Applicable Applications for anti-TM2D1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human TM2D1
Subcellular Location
Membrane; Multipass Membrane Protein
Tissue Specificity
Widely expressed.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog
Similarity
Pig (91%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of TM2D1 using K562 whole cell lysates)
Western Blot (WB)
(Western blot analysis of TM2D1 using K562 whole cell lysates)
Related Product Information for anti-TM2D1 antibody
Function: May participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42.
Subunit Structure: Interacts with APP beta-APP42 (amyloid-beta protein 42).
Post-translational Modifications: N-glycosylated.
Similarity: Belongs to the TM2 family.
Subunit Structure: Interacts with APP beta-APP42 (amyloid-beta protein 42).
Post-translational Modifications: N-glycosylated.
Similarity: Belongs to the TM2 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 22 kDa
Predicted: 23 kDa
Predicted: 23 kDa
NCBI Official Full Name
TM2 domain-containing protein 1
NCBI Official Synonym Full Names
TM2 domain containing 1
NCBI Official Symbol
TM2D1
NCBI Official Synonym Symbols
BBP
NCBI Protein Information
TM2 domain-containing protein 1
UniProt Protein Name
TM2 domain-containing protein 1
Protein Family
UniProt Gene Name
TM2D1
UniProt Synonym Gene Names
BBP; hBBP
NCBI Description
The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]
Uniprot Description
May participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42.
Research Articles on TM2D1
Similar Products
Product Notes
The TM2D1 tm2d1 (Catalog #AAA9610278) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TM2D1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TM2D1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the TM2D1 tm2d1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TM2D1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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