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Immunohistochemistry (IHC) (Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit TM2D1/BBP Polyclonal Antibody | anti-TM2D1/BBP antibody

Anti-TM2D1/BBP Antibody (Internal)

Gene Names
TM2D1; BBP
Reactivity
Human
Predicted: Mouse, Bovine
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
TM2D1/BBP; Polyclonal Antibody; Anti-TM2D1/BBP Antibody (Internal); Rabbit Polyclonal (IgG) to Human TM2D1/BBP; TM2D1; Beta-amyloid-binding protein; BBP; TM2 domain containing 1; HBBP; anti-TM2D1/BBP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Bovine
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of TM2D1 protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.3, 0.01% sodium azide, 30% glycerol.
Sequence Length
207
Applicable Applications for anti-TM2D1/BBP antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100
WB: 1:500-1:1000
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human TM2D1.
Conjugation
Unconjugated
Epitope
Internal
Preparation and Storage
Store at -20 degree C.
Aliquot to avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB)

(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB) (Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of TM2D1 expression in MCF7 (A); mouse kidney (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of TM2D1 expression in MCF7 (A); mouse kidney (B) whole cell lysates.)
Related Product Information for anti-TM2D1/BBP antibody
TM2D1/BBP is a beta-amyloid peptide-binding protein. It contains astructural module related to that of the seven transmembrane domain Gprotein-coupled receptor superfamily and known to be important inheterotrimeric G protein activation. Beta-amyloid peptide has beenestablished to be a causative factor in neuron death and the consequentdiminution of cognitive abilities observed in Alzheimer's disease.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,327 Da
NCBI Official Full Name
TM2 domain-containing protein 1
NCBI Official Synonym Full Names
TM2 domain containing 1
NCBI Official Symbol
TM2D1
NCBI Official Synonym Symbols
BBP
NCBI Protein Information
TM2 domain-containing protein 1
UniProt Protein Name
TM2 domain-containing protein 1
UniProt Gene Name
TM2D1
UniProt Synonym Gene Names
BBP; hBBP

NCBI Description

The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]

Uniprot Description

May participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42.

Research Articles on TM2D1/BBP

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Product Notes

The TM2D1/BBP tm2d1 (Catalog #AAA2401700) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TM2D1/BBP Antibody (Internal) reacts with Human Predicted: Mouse, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's TM2D1/BBP can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the TM2D1/BBP tm2d1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TM2D1/BBP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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