Western Blot (WB)
Rabbit TLR12 Polyclonal Antibody | anti-TLR12 antibody
TLR12 Antibody Affinity Purified
Gene Names
Tlr12; Tlr11; Gm1365
Reactivity
Chimpanzee, Human, Monkey
Applications
ELISA, Western Blot
Synonyms
TLR12; Polyclonal Antibody; TLR12 Antibody Affinity Purified; Toll-like receptor 12; anti-TLR12 antibody
Host
Rabbit
Reactivity
Chimpanzee, Human, Monkey
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.55-0.69 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
906
Applicable Applications for anti-TLR12 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Dot Blot: 1:20,000
ELISA: 1:20,000
Western Blot: 1:500
ELISA: 1:20,000
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid region 440-470 from mouse TLR12 protein.
Expression
Macrophages, liver, kidney and bladder epithelial cells.
Molecular Function
Receptor
Structure
Binds MYD88 via their respective TIR domains.
Subcellular Location
Membrane; Single-pass type I membrane protein
Preparation and Storage
-20 degree C for long term storage
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-TLR12 antibody
Affinity Purified Toll-like receptor 12 Antibody
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Product Categories/Family for anti-TLR12 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
99,945 Da
NCBI Official Full Name
toll-like receptor 12
NCBI Official Synonym Full Names
toll-like receptor 12
NCBI Official Symbol
Tlr12
NCBI Official Synonym Symbols
Tlr11; Gm1365
NCBI Protein Information
toll-like receptor 12
UniProt Protein Name
Toll-like receptor 12
Protein Family
UniProt Gene Name
Tlr12
UniProt Synonym Gene Names
Gm1365
UniProt Entry Name
TLR12_MOUSE
Uniprot Description
TLR12: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in preventing infection of internal organs of the urogenital system. Belongs to the Toll-like receptor family.
Protein type: Receptor, misc.; Membrane protein, integral
Cellular Component: integral to membrane; membrane
Biological Process: defense response to protozoan; immune response; immune system process; inflammatory response; innate immune response; signal transduction
Research Articles on TLR12
Similar Products
Product Notes
The TLR12 tlr12 (Catalog #AAA5400083) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLR12 Antibody Affinity Purified reacts with Chimpanzee, Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's TLR12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Dot Blot: 1:20,000 ELISA: 1:20,000 Western Blot: 1:500. Researchers should empirically determine the suitability of the TLR12 tlr12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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