Rabbit anti-Human, mouse TIMM10B Polyclonal Antibody | anti-TIMM10B antibody

TIMM10B Antibody

Cat. Num. AAA7002260

• Gene Names: TIMM10B; FXC1; Tim9b; TIM10B
• Reactivity: Human, mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >95%,Protein G purified
• Synonyms: TIMM10B; Polyclonal Antibody; TIMM10B Antibody; Mitochondrial import inner membrane translocase subunit Tim10 B; Fracture callus protein 1; FxC1; Mitochondrial import inner membrane translocase subunit Tim9 B; Tim10b; FXC1; TIM9B; TIMM9B; anti-TIMM10B antibody

• Host: Rabbit
• Reactivity: Human, mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 103

• Applicable Applications for anti-TIMM10B antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Recombinant human Mitochondrial import inner membrane translocase subunit Tim10 B protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-17062 / sc-17063
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western blotAll lanes: TIMM10B antibody at 4ug/mlLane 1: Hela whole cell lysateLane 2: 293T whole cell lysateLane 3: HepG-2 whole cell lysateLane 4: K562 whole cell lysateLane 5: Mouse heart tissueSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 12 kDaObserved band size: 12 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7002260 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7002260 at dilution of 1:100)

Related Product Information for anti-TIMM10B antibody

Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.

NCBI and Uniprot Product Information

• NCBI GI #: 6912382
• NCBI GeneID: 26515
• NCBI Accession #: NP_036324.1
• NCBI GenBank Nucleotide #: NM_012192.3
• UniProt Accession #: Q9Y5J6; Q96FF3
• Molecular Weight: 11,586 Da
• NCBI Official Full Name: mitochondrial import inner membrane translocase subunit Tim10 B
• NCBI Official Synonym Full Names: translocase of inner mitochondrial membrane 10 homolog B (yeast)
• NCBI Official Symbol: TIMM10B
• NCBI Official Synonym Symbols: FXC1; Tim9b; TIM10B
• NCBI Protein Information: mitochondrial import inner membrane translocase subunit Tim10 B
• UniProt Protein Name: Mitochondrial import inner membrane translocase subunit Tim10 B
• Protein Family: Mitochondrial import inner membrane translocase
• UniProt Gene Name: TIMM10B
• UniProt Synonym Gene Names: FXC1; TIM9B; TIMM9B; Tim10b
• UniProt Entry Name: T10B_HUMAN

NCBI Description

FXC1, or TIMM10B, belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004]

Uniprot Description

TIMM10B: Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space. Belongs to the small Tim family.

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial intermembrane space protein transporter complex

Molecular Function: metal ion binding

Biological Process: cell-matrix adhesion; cellular protein metabolic process; protein targeting to mitochondrion