Goat anti-Mouse Thymic Stromal Lymphopoietin Protein Receptor Polyclonal Antibody | anti-TSLP antibody

Thymic Stromal Lymphopoietin Protein Receptor (TSLP R) (Carboxyfluorescein) (CFS)

Cat. Num. AAA610926

• Gene Names: TSLP; TSLP
• Reactivity: Mouse
• Applications: Flow Cytometry, Functional Assay
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Thymic Stromal Lymphopoietin Protein Receptor; Polyclonal Antibody; Thymic Stromal Lymphopoietin Protein Receptor (TSLP R) (Carboxyfluorescein) (CFS); Anti -Thymic Stromal Lymphopoietin Protein Receptor (TSLP R) (Carboxyfluorescein) (CFS); anti-TSLP antibody

• Host: Goat
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes mouse TSLP R.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Suppled as a liquid in PBS, 0.1% sodium azide. Labeled with Carboxyfluorescein (CFS).

• Applicable Applications for anti-TSLP antibody: Flow Cytometry (FC/FACS)
• Application Notes: Suitable for use in Flow Cytometry.; Dilution: Flow Cytometry: 10ul per test
• Immunogen: Recombinant protein corresponding to aa20-233 of mouse TSLP R expressed in NSO cells.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Carboxyfluorescein conjugates are sensitive to light.

Related Product Information for anti-TSLP antibody

TSLP R associates with IL-7 R alpha to form a heterodimeric receptor complex for TSLP. TSLP R signaling is involved in the stimulation of thymocyte and mature T cell growth and the support of B cell lymphopoiesis.

Product Categories/Family for anti-TSLP antibody

Antibodies; Abs to CD Markers

NCBI and Uniprot Product Information

• NCBI GI #: 14719428
• NCBI GeneID: 85480
• NCBI Accession #: NP_149024.1
• NCBI GenBank Nucleotide #: NM_033035.4
• UniProt Accession #: Q969D9; Q8IW99; Q96AU7
• Molecular Weight: 18,141 Da
• NCBI Official Full Name: thymic stromal lymphopoietin
• NCBI Official Synonym Full Names: thymic stromal lymphopoietin
• NCBI Official Symbol: TSLP
• NCBI Official Synonym Symbols: TSLP
• NCBI Protein Information: thymic stromal lymphopoietin; OTTHUMP00000158998; OTTHUMP00000158999
• UniProt Protein Name: Thymic stromal lymphopoietin
• Protein Family: Thymic stromal lymphopoietin
• UniProt Gene Name: TSLP
• UniProt Entry Name: TSLP_HUMAN

NCBI Description

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq]

Uniprot Description

TSLP: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 5q22.1

Cellular Component: extracellular space

Molecular Function: cytokine activity