Rabbit anti-Rat Thrombospondin 4 (THBS4) Polyclonal Antibody | anti-THBS4 antibody
FITC-linked Antibody to Thrombospondin 4 (THBS4)
Immunohistochemistry: 5-20 ug/mL;1:10-40
Immunocytochemistry: 5-20 ug/mL;1:10-40
Optimal working dilutions must be determined by end user.
Store at 4°C for frequent use.
Aliquot and store at -20°C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. This gene is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Uniprot Description
THBS4: Acts as an extracellular mitogen and stimulates early erythroid progenitors proliferation in presence of EPO. Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen. Belongs to the thrombospondin family.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q13
Cellular Component: extracellular matrix; extracellular space; sarcoplasmic reticulum; endoplasmic reticulum; extracellular region; basement membrane
Molecular Function: heparin binding; integrin binding; protein binding; growth factor activity; calcium ion binding
Biological Process: behavioral response to pain; negative regulation of angiogenesis; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of cell division; tissue remodeling; myoblast migration; positive regulation of endothelial cell proliferation; response to unfolded protein; regulation of tissue remodeling
Research Articles on THBS4
Similar Products
Product Notes
The THBS4 thbs4 (Catalog #AAA2018050) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FITC-linked Antibody to Thrombospondin 4 (THBS4) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Thrombospondin 4 (THBS4) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF). Western blotting: 0.5-2 ug/mL;1:100-400 Immunohistochemistry: 5-20 ug/mL;1:10-40 Immunocytochemistry: 5-20 ug/mL;1:10-40 Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the THBS4 thbs4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thrombospondin 4 (THBS4), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
