Rabbit anti-Human THRAP3 Polyclonal Antibody | anti-THRAP3 antibody

THRAP3, CT (THRAP3, TRAP150, Thyroid hormone receptor-associated protein 3, Thyroid hormone receptor-associated protein complex 150kD component) (FITC)

Cat. Num. AAA6355473

• Gene Names: THRAP3; TRAP150
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: THRAP3; Polyclonal Antibody; CT (THRAP3; TRAP150; Thyroid hormone receptor-associated protein 3; Thyroid hormone receptor-associated protein complex 150kD component) (FITC); Thyroid hormone receptor-associated protein complex 150kD component; anti-THRAP3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-THRAP3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: THRAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 926-955 amino acids from the C-terminal region of human THRAP3.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(THRAP3 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the THRAP3 antibody detected the THRAP3 protein (arrow).)

Related Product Information for anti-THRAP3 antibody

THRAP3 plays a role in transcriptional coactivation.

Product Categories/Family for anti-THRAP3 antibody

Antibodies; Receptors

References

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Olsen, J.V., et al. Cell 127(3):635-648(2006). Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006). Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006). Jin, J., et al. Curr. Biol. 14(16):1436-1450(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 167234419
• NCBI GeneID: 9967
• NCBI Accession #: NP_005110.2
• NCBI GenBank Nucleotide #: NM_005119.3
• UniProt Accession #: Q9Y2W1; Q5VTK6; D3DPS5
• Molecular Weight: 108,666 Da
• NCBI Official Full Name: thyroid hormone receptor-associated protein 3
• NCBI Official Synonym Full Names: thyroid hormone receptor associated protein 3
• NCBI Official Symbol: THRAP3
• NCBI Official Synonym Symbols: TRAP150
• NCBI Protein Information: thyroid hormone receptor-associated protein 3; thyroid hormone receptor-associated protein, 150 kDa subunit; thyroid hormone receptor-associated protein complex 150 kDa component
• UniProt Protein Name: Thyroid hormone receptor-associated protein 3
• Protein Family: Thyroid hormone receptor-associated protein
• UniProt Gene Name: THRAP3
• UniProt Synonym Gene Names: TRAP150; Trap150
• UniProt Entry Name: TR150_HUMAN

Uniprot Description

Trap150: Plays a role in transcriptional coactivation.

Protein type: Transcription, coactivator/corepressor; RNA-binding

Chromosomal Location of Human Ortholog: 1p34.3

Cellular Component: nucleoplasm; Srb-mediator complex; nucleus

Molecular Function: protein binding; ligand-dependent nuclear receptor transcription coactivator activity; vitamin D receptor binding; transcription coactivator activity; transcription cofactor activity; phosphoprotein binding; thyroid hormone receptor binding; receptor activity; ATP binding

Biological Process: steroid hormone receptor signaling pathway; positive regulation of nuclear mRNA splicing, via spliceosome; transcription initiation from RNA polymerase II promoter; mRNA stabilization; positive regulation of transcription, DNA-dependent; RNA splicing; androgen receptor signaling pathway; rhythmic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of circadian rhythm; mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome