Rabbit TGF beta Receptor III Polyclonal Antibody | anti-TGFBR3 antibody
TGF beta Receptor III (Phospho-Thr842) Antibody
Gene Names
TGFBR3; BGCAN; betaglycan
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Synonyms
TGF beta Receptor III; Polyclonal Antibody; TGF beta Receptor III (Phospho-Thr842) Antibody; anti-TGFBR3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
TGF beta Receptor III (Phospho-Thr842) Antibody detects endogenous levels of TGF beta Receptor III only when phosphorylated at Thr842.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
850
Applicable Applications for anti-TGFBR3 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
IHC: 1:50~1:100
IF: 1:100~1:1000
ELISA: 1:10000
IF: 1:100~1:1000
ELISA: 1:10000
Target Modification
Phospho
Modification Sites
H:T842; M:T842; R:T845
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor III around the phosphorylation site of Thr842.
Immunogen Range
801-850
Preparation and Storage
Stable at -20 degree C for at least 1 year.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
93 kDa
NCBI Official Full Name
transforming growth factor beta receptor type 3 isoform b
NCBI Official Synonym Full Names
transforming growth factor beta receptor 3
NCBI Official Symbol
TGFBR3
NCBI Official Synonym Symbols
BGCAN; betaglycan
NCBI Protein Information
transforming growth factor beta receptor type 3
UniProt Protein Name
Transforming growth factor beta receptor type 3
Protein Family
UniProt Gene Name
TGFBR3
UniProt Synonym Gene Names
TGF-beta receptor type 3; TGFR-3; TGF-beta receptor type III
NCBI Description
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
Uniprot Description
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
Research Articles on TGFBR3
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Product Notes
The TGFBR3 tgfbr3 (Catalog #AAA9502881) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TGF beta Receptor III (Phospho-Thr842) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TGF beta Receptor III can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). IHC: 1:50~1:100 IF: 1:100~1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the TGFBR3 tgfbr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGF beta Receptor III, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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