Rabbit TGF beta 3 Polyclonal Antibody | anti-TGF beta 3 antibody
TGF beta 3 antibody
Gene Names
TGFBR3; BGCAN; betaglycan
Applications
Western Blot
Purity
Purified by peptide affinity purification.
Synonyms
TGF beta 3; Polyclonal Antibody; TGF beta 3 antibody; Rabbit polyclonal TGF beta 3 antibody; Polyclonal TGF beta 3 antibody; Anti-TGF beta 3 antibody; TGF-beta-3 antibody; Transforming growth factor 3 antibody; Tumor growth factor 3 antibody; TGF beta-3; TGF beta-3 antibody; anti-TGF beta 3 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by peptide affinity purification.
Form/Format
Supplied in PBS buffer containing 30% glycerol,0.5% BSA, and 0.01% thimerosal.
Concentration
500 ug/ml (varies by lot)
Sequence Length
850
Applicable Applications for anti-TGF beta 3 antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Immunogen
TGF beta 3 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 254of human TGF-beta 3 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat
Preparation and Storage
Store at-20 degree C. For long-term storage, aliquot and freeze at-70 degree C.
Avoid repeated freeze/thaw cycles.
Avoid repeated freeze/thaw cycles.
Related Product Information for anti-TGF beta 3 antibody
The three mammalian isoforms of TGF beta (TGF beta1, TGF beta2, TGF beta3) signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and would healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF beta isoform from a latent complex involves proteolytic processing of the complex and/or induction of conformational changes by proteins such as thrombospondin 1. TGF beta2 has been shown to exert suppressive effects on IL 2 dependent T cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno surveillance of tumor development.
Product Categories/Family for anti-TGF beta 3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
93,428 Da
NCBI Official Full Name
transforming growth factor beta receptor type 3 isoform b
NCBI Official Synonym Full Names
transforming growth factor beta receptor 3
NCBI Official Symbol
TGFBR3
NCBI Official Synonym Symbols
BGCAN; betaglycan
NCBI Protein Information
transforming growth factor beta receptor type 3
UniProt Protein Name
Transforming growth factor beta receptor type 3
UniProt Gene Name
TGFBR3
UniProt Synonym Gene Names
TGF-beta receptor type 3; TGFR-3; TGF-beta receptor type III
NCBI Description
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
Uniprot Description
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
Research Articles on TGF beta 3
Similar Products
Product Notes
The TGF beta 3 tgfbr3 (Catalog #AAA5309190) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TGF beta 3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the TGF beta 3 tgfbr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGF beta 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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