Rabbit anti-Mouse Cdkl5 Polyclonal Antibody | anti-Cdkl5 antibody

Cdkl5, CT (Cdkl5, Cyclin-dependent kinase-like 5) (FITC)

Cat. Num. AAA6284581

• Gene Names: Cdkl5; Stk9; BC038161
• Reactivity: Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: Cdkl5; Polyclonal Antibody; CT (Cdkl5; Cyclin-dependent kinase-like 5) (FITC); Cyclin-dependent kinase-like 5; anti-Cdkl5 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-Cdkl5 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Mouse Cdkl5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 729-758 amino acids from the C-terminal region of human Mouse Cdkl5.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Mouse Cdkl5 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Cdkl5 antibody detected the Cdkl5 protein (arrow).)

Related Product Information for anti-Cdkl5 antibody

Cdkl5 mediates phosphorylation of MECP2 (By similarity).

Product Categories/Family for anti-Cdkl5 antibody

Antibodies; Protein Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 124244037
• NCBI GeneID: 382253
• NCBI Accession #: NP_001019795.1
• NCBI GenBank Nucleotide #: NM_001024624.2
• UniProt Accession #: Q3UTQ8; Q05BK3; Q8BWI8
• Molecular Weight: 59,784 Da
• NCBI Official Full Name: cyclin-dependent kinase-like 5
• NCBI Official Synonym Full Names: cyclin-dependent kinase-like 5
• NCBI Official Symbol: Cdkl5
• NCBI Official Synonym Symbols: Stk9; BC038161
• NCBI Protein Information: cyclin-dependent kinase-like 5
• UniProt Protein Name: Cyclin-dependent kinase-like 5
• Protein Family: Cyclin-dependent kinase
• UniProt Gene Name: Cdkl5
• UniProt Entry Name: CDKL5_MOUSE

Uniprot Description

CDKL5: a protein kinase of the CDKL family. Mutations have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.

Protein type: Kinase, protein; Protein kinase, CMGC; Cell cycle regulation; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.22; CMGC group; CDKL family

Cellular Component: dendrite cytoplasm; nucleoplasm; cytoplasm; nucleus

Molecular Function: transferase activity; protein serine/threonine kinase activity; cyclin-dependent protein kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; Rac GTPase binding; kinase activity; ATP binding; protein kinase activity

Biological Process: protein amino acid autophosphorylation; positive regulation of axon extension; neuron migration; regulation of dendrite development; positive regulation of dendrite morphogenesis; protein amino acid phosphorylation; phosphorylation