Rabbit TFIP11 Polyclonal Antibody | anti-TFIP11 antibody
TFIP11 Antibody
Gene Names
TFIP11; NTR1; TIP39; hNtr1; Spp382; bK445C9.6
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
TFIP11; Polyclonal Antibody; TFIP11 Antibody; BK445C9.6; DKFZP434B194; FLJ22086; HNtr1; NTR1; S. cerevisiae; homolog of; OTTHUMP00000198650; OTTHUMP00000198850; OTTHUMP00000198851; OTTHUMP00000198852; Septin and tuftelin-interacting protein 1; Spp382; STIP; STIP-1; TFP11_HUMAN; TIP39; Tuftelin interacting protein 11; Tuftelin-interacting protein 11; 39-KD; anti-TFIP11 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
TFIP11 Antibody detects endogenous levels of total TFIP11.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-TFIP11 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Similarity
Belongs to the TFP11/STIP family.
Subunit Structure
Identified in the spliceosome C complex. Found in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors. Interacts with TUFT1. Interacts with DHX15; indicative for a recruitment of DHX15 to the IL complex. Interacts with GCFC2.
Function
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
Note
In the nucleus localizes to unique speckle domains in close proximity to nuclear speckles and not identical to paraspeckles.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
96,820 Da
NCBI Official Full Name
tuftelin-interacting protein 11
NCBI Official Synonym Full Names
tuftelin interacting protein 11
NCBI Official Symbol
TFIP11
NCBI Official Synonym Symbols
NTR1; TIP39; hNtr1; Spp382; bK445C9.6
NCBI Protein Information
tuftelin-interacting protein 11; STIP-1; septin and tuftelin-interacting protein 1
UniProt Protein Name
Tuftelin-interacting protein 11
Protein Family
UniProt Gene Name
TFIP11
UniProt Synonym Gene Names
STIP; HSPC006; STIP-1
UniProt Entry Name
TFP11_HUMAN
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Product Notes
The TFIP11 tfip11 (Catalog #AAA9629127) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TFIP11 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TFIP11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the TFIP11 tfip11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TFIP11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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