Typical Testing Data/Standard Curve (for reference only)
(Human Tetranectin/CLEC3B PicoKine ELISA Kit standard curve )
Human Tetranectin/CLEC3B ELISA Kit | CLEC3B elisa kit
Human Tetranectin/CLEC3B PicoKine ELISA Kit
Gene Names
CLEC3B; TN; TNA
Reactivity
Human
Synonyms
Tetranectin/CLEC3B; Human Tetranectin/CLEC3B PicoKine ELISA Kit; Tetranectin; C-type lectin domain family 3; member B; C type lectin domain family 3 member B; C-type lectin domain family 3 member B; Clec3b; Plasminogen kringle 4 binding protein; Plasminogen kringle 4-binding protein; TETN_HUMAN; Tetranectin (plasminogen binding protein); TN; TNA; CLEC3B elisa kit
Reactivity
Human
Specificity
Natural and recombinant human Tetranectin
Sequence Length
202
Samples
Cell culture supernates, serum and tissue Homogenates
Assay Type
Sandwich
Detection Range
312pg/ml-20,000pg/ml
Sensitivity
< 10pg/ml
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Typical Testing Data/Standard Curve (for reference only)
(Human Tetranectin/CLEC3B PicoKine ELISA Kit standard curve )
Typical Testing Data/Standard Curve (for reference only)
(Human Tetranectin/CLEC3B PicoKine ELISA Kit standard curve )
Related Product Information for CLEC3B elisa kit
Principle of the assay: human Tetranectin ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for Tetranectin has been precoated onto 96-well plates. Standards(NSO, E22-V202) and test samples are added to the wells; a biotinylated detection polyclonal antibody from goat specific for Tetranectin is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human Tetranectin amount of sample captured in plate.
Background: Tetranectin, also called TNA, is a protein that in humans is encoded by the CLEC3B gene. It is mapped to 3p21.31. Tetranectin, a tetrameric protein isolated from human plasma, has 4 identical and noncovalently bound polypeptide chains, each of 181 amino acid residues. It has a specific binding affinity for sulfated polysaccharides and the kringle 4 of plasminogen. The plasma concentration of tetranectin is reduced in patients with various malignancies. Tetranectin is a plasminogen-binding protein that is induced during the mineralization phase of osteogenesis. Thus, tetranectin is a candidate gene for human disorders affecting bone and connective tissue.
Background: Tetranectin, also called TNA, is a protein that in humans is encoded by the CLEC3B gene. It is mapped to 3p21.31. Tetranectin, a tetrameric protein isolated from human plasma, has 4 identical and noncovalently bound polypeptide chains, each of 181 amino acid residues. It has a specific binding affinity for sulfated polysaccharides and the kringle 4 of plasminogen. The plasma concentration of tetranectin is reduced in patients with various malignancies. Tetranectin is a plasminogen-binding protein that is induced during the mineralization phase of osteogenesis. Thus, tetranectin is a candidate gene for human disorders affecting bone and connective tissue.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
22,537 Da
NCBI Official Full Name
Tetranectin
NCBI Official Synonym Full Names
C-type lectin domain family 3, member B
NCBI Official Symbol
CLEC3B
NCBI Official Synonym Symbols
TN; TNA
NCBI Protein Information
tetranectin; plasminogen kringle 4-binding protein; tetranectin (plasminogen binding protein); tetranectin (plasminogen-binding protein)
UniProt Protein Name
Tetranectin
Protein Family
UniProt Gene Name
CLEC3B
UniProt Synonym Gene Names
TNA; TN
UniProt Entry Name
TETN_HUMAN
Uniprot Description
CLEC3B: Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3p22-p21.3
Cellular Component: extracellular matrix; extracellular space; granular component; cytoplasm; extracellular region
Molecular Function: heparin binding; calcium ion binding; carbohydrate binding
Biological Process: ossification; skeletal development; bone mineralization
Research Articles on CLEC3B
Similar Products
Product Notes
The Human CLEC3B clec3b (Catalog #AAA177384) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA177384 ELISA Kit recognizes Human CLEC3B. It is sometimes possible for the material contained within the vial of "Tetranectin/CLEC3B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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