Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using TESC Polyclonal Antibody at dilution of 1:25(×200))
Rabbit anti-Human, Mouse TESC Polyclonal Antibody | anti-TESC antibody
TESC Polyclonal Antibody
Gene Names
TESC; TSC; CHP3
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
TESC; Polyclonal Antibody; TESC Polyclonal Antibody; 1010001A17Rik; Calcineurin B homologous protein 3; CHP3; FLJ20607; MGC117906; OTTHUMP00000185561; OTTMUSP00000023573; TE 1; Tescalcin; TSC; anti-TESC antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.6mg/mL (varies by lot)
Sequence Length
187
Applicable Applications for anti-TESC antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:25-1:100
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human TESC
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using TESC Polyclonal Antibody at dilution of 1:25(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using TESC Polyclonal Antibody at dilution of 1:25(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human tonsil tissue using TESC Polyclonal Antibody at dilution of 1:25(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human tonsil tissue using TESC Polyclonal Antibody at dilution of 1:25(×200))
Related Product Information for anti-TESC antibody
Tescalcin, also known as TESC, TSC or CHP3, is a 267 amino acid protein that contains one EF-hand domain and is expressed abundantly in adult heart tissue. Using calcium as a cofactor, Tescalcin interacts with NHE-1 and functions to couple the activation of the ERK cascade with the expression of Ets proteins during megakaryocytic differentiation. Human Tescalcin shares 97% sequence identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of Tescalcin exist due to alternative splicing events. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.
Product Categories/Family for anti-TESC antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
calcineurin B homologous protein 3 isoform 2
NCBI Official Synonym Full Names
tescalcin
NCBI Official Symbol
TESC
NCBI Official Synonym Symbols
TSC; CHP3
NCBI Protein Information
calcineurin B homologous protein 3
UniProt Protein Name
Calcineurin B homologous protein 3
Protein Family
UniProt Gene Name
TESC
UniProt Synonym Gene Names
CHP3; TSC
UniProt Entry Name
CHP3_HUMAN
Research Articles on TESC
Similar Products
Product Notes
The TESC tesc (Catalog #AAA2562233) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TESC Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TESC can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:25-1:100 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the TESC tesc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TESC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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