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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS7049252 at dilution of 1:100)

Rabbit anti-Human TECPR2 Polyclonal Antibody | anti-TECPR2 antibody

TECPR2 Antibody

Gene Names
TECPR2; SPG49; KIAA0329
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
TECPR2; Polyclonal Antibody; TECPR2 Antibody; Tectonin beta-propeller repeat-containing protein 2; WD repeat-containing protein KIAA0329/KIAA0297; KIAA0297; KIAA0329; anti-TECPR2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
1267
Applicable Applications for anti-TECPR2 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1: 20-1: 200
IF: 1: 50-1: 200
Immunogen
Recombinant Human Tectonin beta-propeller repeat-containing protein 2 protein (516-783AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS7049252 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS7049252 at dilution of 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of PC3 cells using MBS7049252 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunofluorescence (IF) (Immunofluorescent analysis of PC3 cells using MBS7049252 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-TECPR2 antibody
Probably plays a role as positive regulator of autophagy.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
tectonin beta-propeller repeat-containing protein 2 isoform 2
NCBI Official Synonym Full Names
tectonin beta-propeller repeat containing 2
NCBI Official Symbol
TECPR2
NCBI Official Synonym Symbols
SPG49; KIAA0329
NCBI Protein Information
tectonin beta-propeller repeat-containing protein 2
UniProt Protein Name
Tectonin beta-propeller repeat-containing protein 2
UniProt Gene Name
TECPR2
UniProt Synonym Gene Names
KIAA0297; KIAA0329
UniProt Entry Name
TCPR2_HUMAN

NCBI Description

The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]

Uniprot Description

TECPR2: Belongs to the WD repeat KIAA0329 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 14q32.31

Molecular Function: protein binding

Disease: Spastic Paraplegia 49, Autosomal Recessive

Research Articles on TECPR2

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Product Notes

The TECPR2 tecpr2 (Catalog #AAA7049252) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TECPR2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TECPR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1: 20-1: 200 IF: 1: 50-1: 200. Researchers should empirically determine the suitability of the TECPR2 tecpr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TECPR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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