Western Blot (WB)
(Western blot analysis of Thymine DNA Glycosylase expression in HeLa (A); mouse lung (B); rat lung (C) whole cell lysates.)
Rabbit TDG Polyclonal Antibody | anti-TDG antibody
TDG Antibody
Gene Names
TDG; hTDG
Applications
Western Blot, Immunofluorescence, Immunocytochemistry
Purity
Immunogen Affinity Chromatography
Synonyms
TDG; Polyclonal Antibody; TDG Antibody; Purified Polyclonal TDG Antibody; Polyclonal TDG antibody; Anti-TDG antibody; G/T mismatch-specific thymine DNA glycosylase antibody; Thymine-DNA glycosylase antibody; hTDG antibody; anti-TDG antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Thymine DNA Glycosylase protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
382
Applicable Applications for anti-TDG antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes
WB: 1:500-1:1000
IF: 1:100-1:500
ICC: 1:100-1:500
IF: 1:100-1:500
ICC: 1:100-1:500
Immunogen
TDG antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Thymine DNA Glycosylase as the immunogen
Cross-Reactivity
Mouse, Rat, Bovine
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Thymine DNA Glycosylase expression in HeLa (A); mouse lung (B); rat lung (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Thymine DNA Glycosylase expression in HeLa (A); mouse lung (B); rat lung (C) whole cell lysates.)
Related Product Information for anti-TDG antibody
TDG belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings.
Product Categories/Family for anti-TDG antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
TDG protein, partial
NCBI Official Synonym Full Names
thymine DNA glycosylase
NCBI Official Symbol
TDG
NCBI Official Synonym Symbols
hTDG
NCBI Protein Information
G/T mismatch-specific thymine DNA glycosylase
Protein Family
NCBI Description
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
Research Articles on TDG
Similar Products
Product Notes
The TDG (Catalog #AAA5316268) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TDG can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC). WB: 1:500-1:1000 IF: 1:100-1:500 ICC: 1:100-1:500. Researchers should empirically determine the suitability of the TDG for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TDG, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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