Western Blot (WB)
(FGF7 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FGF7 antibody detected the FGF7 protein (arrow).)
Rabbit FGF7 Polyclonal Antibody | anti-FGF7 antibody
FGF7 Antibody (Center)
Western Blot (WB)
(FGF7 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FGF7 antibody detected the FGF7 protein (arrow).)
Western Blot (WB)
(FGF7 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FGF7 antibody detected the FGF7 protein (arrow).)
Immunohistochemistry (IHC)
(FGF7 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human M.heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FGF7 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(FGF7 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human M.heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FGF7 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
fibroblast growth factor (FGF) family. FGF family members possess
broad mitogenic and cell survival activities, and are involved in a
variety of biological processes, including embryonic development,
cell growth, morphogenesis, tissue repair, tumor growth and
invasion. This protein is a potent epithelial cell-specific growth
factor, whose mitogenic activity is predominantly exhibited in
keratinocytes but not in fibroblasts and endothelial cells. Studies
of mouse and rat homologs of this gene implicated roles in
morphogenesis of epithelium, reepithelialization of wounds, hair
development and early lung organogenesis.
Bando, M., et al. Immunol. Cell Biol. 88(3):328-333(2010)
Wang, X., et al. Biomaterials 31(9):2542-2548(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Aguilar, S., et al. PLoS ONE 4 (11), E8013 (2009) :
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
FGF7: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. Belongs to the heparin-binding growth factors family.
Protein type: Secreted; Cytokine; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 15q21.2
Cellular Component: Golgi apparatus; extracellular region
Molecular Function: heparin binding; protein binding; growth factor activity; chemoattractant activity; fibroblast growth factor receptor binding
Biological Process: positive regulation of keratinocyte migration; epidermal growth factor receptor signaling pathway; epidermis development; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; hair follicle morphogenesis; nerve growth factor receptor signaling pathway; mesenchymal cell proliferation; signal transduction; positive regulation of peptidyl-tyrosine phosphorylation; positive chemotaxis; positive regulation of cell division; positive regulation of cell proliferation; actin cytoskeleton reorganization; response to wounding; insulin receptor signaling pathway; innate immune response; positive regulation of epithelial cell proliferation
Research Articles on FGF7
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Product Notes
The FGF7 fgf7 (Catalog #AAA9212851) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 57-86. The FGF7 Antibody (Center) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's FGF7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the FGF7 fgf7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FGF7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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