Rabbit anti-Human TCRB Polyclonal Antibody | anti-TCRB antibody

TCRB, ID (TCRB, T-cell receptor beta chain V region CTL-L17) (Biotin)

Cat. Num. AAA6354592

• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TCRB; Polyclonal Antibody; ID (TCRB; T-cell receptor beta chain V region CTL-L17) (Biotin); T-cell receptor beta chain V region CTL-L17; anti-TCRB antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-TCRB antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: TCRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the Central region of human TCRB.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TCRB Antibody (Center) western blot analysis in MDA-MB231,293,Ramos,NCI-H460 cell line lysates (35ug/lane).This demonstrates the TCRB antibody detected the TCRB protein (arrow).)

Related Product Information for anti-TCRB antibody

The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.

Product Categories/Family for anti-TCRB antibody

Antibodies; Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 136494
• UniProt Accession #: P04435
• Molecular Weight: 14,999 Da
• NCBI Official Full Name: T-cell receptor beta chain V region CTL-L17
• UniProt Protein Name: T-cell receptor beta chain V region CTL-L17
• Protein Family: T-cell receptor
• UniProt Gene Name: TCRB

Uniprot Description

MiscellaneousThis sequence was derived from a human cytotoxic T-lymphocyte that is T3+, T4+, T8-.