Western Blot (WB)
(Western Blot analysis in K562 cell line lysates (35ug) using MBS648639. This demonstrates that MBS648639 detected the PTCRA protein (arrow).)
Rabbit anti-Human PTCRA Polyclonal Antibody | anti-Ptcra antibody
PTCRA, CT (PTCRA, Pre T-cell antigen receptor alpha, pT-alpha-TCR)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(Western Blot analysis in K562 cell line lysates (35ug) using MBS648639. This demonstrates that MBS648639 detected the PTCRA protein (arrow).)
Western Blot (WB)
(Western Blot analysis in K562 cell line lysates (35ug) using MBS648639. This demonstrates that MBS648639 detected the PTCRA protein (arrow).)
NCBI and Uniprot Product Information
Uniprot Description
Function: The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. Isoform 1 acts to retain most TCRB intracellularly, while isoform 2 permits higher levels of cell surface TCRB expression and facilitates signaling from the CD3-TCRB complex. Ref.3
Subunit structure: Interacts with RHBDD1
By similarity. Heterodimer with TCRB; disulfide linked. This heterodimer assembles with CD3 proteins into a signaling-competent pre-T-cell receptor complex. Ref.1
Subcellular location: Membrane; Single-pass type I membrane protein
Potential.
Tissue specificity: Isoform 1 is expressed at higher levels than isoform 2 in the thymus while only isoform 2 is expressed in polyclonal beta-only cells. Isoform 1 shows a predominant expression in immature thymocytes. Ref.1 Ref.3
Sequence caution: The sequence AAA58963.1 differs from that shown. Reason: Erroneous initiation. The sequence AAI19063.1 differs from that shown. Reason: Erroneous initiation. The sequence AAI20747.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on Ptcra
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Product Notes
The Ptcra ptcra (Catalog #AAA648639) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTCRA, CT (PTCRA, Pre T-cell antigen receptor alpha, pT-alpha-TCR) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTCRA can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the Ptcra ptcra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTCRA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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