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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis using MBS1493839 at dilution of 1:100)

Rabbit anti-Human TCN1 Polyclonal Antibody | anti-TCN1 antibody

TCN1 Antibody

Gene Names
TCN1; HC; TC1; TCI; TC-1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%, Protein G Purified
Synonyms
TCN1; Polyclonal Antibody; TCN1 Antibody; Transcobalamin-1; TC-1; TC1; Haptocorrin; HC; Protein R; Transcobalamin I; TC I; TCI; anti-TCN1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
433
Applicable Applications for anti-TCN1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC:1:20-1:200
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Transcobalamin-1 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47511 / sc-47509 / sc-98966
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis using MBS1493839 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis using MBS1493839 at dilution of 1:100)
Related Product Information for anti-TCN1 antibody
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,207 Da
NCBI Official Full Name
transcobalamin-1
NCBI Official Synonym Full Names
transcobalamin 1
NCBI Official Symbol
TCN1
NCBI Official Synonym Symbols
HC; TC1; TCI; TC-1
NCBI Protein Information
transcobalamin-1
UniProt Protein Name
Transcobalamin-1
Protein Family
UniProt Gene Name
TCN1
UniProt Synonym Gene Names
TC1; TC-1; HC; TC I; TCI
UniProt Entry Name
TCO1_HUMAN

NCBI Description

This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq, Jul 2008]

Uniprot Description

TCN1: Vitamin B12-binding protein. Transports cobalamin into cells. Belongs to the eukaryotic cobalamin transport proteins family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11q11-q12

Cellular Component: extracellular region; extracellular space

Molecular Function: cobalamin binding

Biological Process: cobalamin metabolic process; cobalamin transport; cobalt ion transport; vitamin metabolic process; water-soluble vitamin metabolic process

Research Articles on TCN1

Similar Products

Product Notes

The TCN1 tcn1 (Catalog #AAA1493839) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TCN1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TCN1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC:1:20-1:200. Researchers should empirically determine the suitability of the TCN1 tcn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TCN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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