Western Blot (WB)
(TCEA2 Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the TCEA2 antibody detected the TCEA2 protein (arrow).)
Rabbit anti-Human TCEA2 Polyclonal Antibody | anti-TCEA2 antibody
TCEA2 Antibody (Center)
Western Blot (WB)
(TCEA2 Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the TCEA2 antibody detected the TCEA2 protein (arrow).)
Western Blot (WB)
(TCEA2 Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the TCEA2 antibody detected the TCEA2 protein (arrow).)
where it functions as an SII class transcription elongation factor.
Elongation factors in this class are responsible for releasing RNA
polymerase II ternary complexes from transcriptional arrest at
template-encoded arresting sites. The encoded protein has been
shown to interact with general transcription factor IIB, a basal
transcription factor. Two transcript variants encoding different
isoforms have been found for this gene.
Palangat, M., et al. Proc. Natl. Acad. Sci. U.S.A. 102(42):15036-15041(2005)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Nakata, A., et al. Genes Cells 9(11):1125-1135(2004)
Tamura, K., et al. Biochem. Biophys. Res. Commun. 309(1):189-195(2003)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
TCEA2: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. Belongs to the TFS-II family.
Chromosomal Location of Human Ortholog: 20q13.33
Cellular Component: nucleoplasm; centrosome; transcription elongation factor complex
Molecular Function: protein binding; DNA binding; zinc ion binding
Biological Process: RNA elongation; positive regulation of transcription from RNA polymerase II promoter; regulation of RNA elongation
Research Articles on TCEA2
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Product Notes
The TCEA2 tcea2 (Catalog #AAA9207644) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 86-115. The TCEA2 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TCEA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the TCEA2 tcea2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TCEA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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