Rabbit anti-Human TBX18 Polyclonal Antibody | anti-TBX18 antibody

TBX18 Antibody

Cat. Num. AAA7131660

• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: TBX18; Polyclonal Antibody; TBX18 Antibody; T-box protein 18; T-box Transcription factor TBX18; anti-TBX18 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid; Rabbit IgG In Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.

• Applicable Applications for anti-TBX18 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:500-1:3000
• Immunogen: Synthesized peptide derived from internal of human TBX18.
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blot analysis of extracts from Jurkat cells, using TBX18 antibody. )

Product Categories/Family for anti-TBX18 antibody

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 122937456
• NCBI GeneID: 9096
• NCBI Accession #: NP_001073977.1
• NCBI GenBank Nucleotide #: NM_001080508.2
• UniProt Accession #: O95935; Q7Z6U4; Q9UJI6; A2RU13
• Molecular Weight: 64,753 Da
• NCBI Official Full Name: T-box transcription factor TBX18
• NCBI Official Synonym Full Names: T-box 18
• NCBI Official Symbol: TBX18
• NCBI Protein Information: T-box transcription factor TBX18; T-box protein 18
• UniProt Protein Name: T-box transcription factor TBX18
• Protein Family: T-box transcription factor
• UniProt Gene Name: TBX18
• UniProt Synonym Gene Names: T-box protein 18
• UniProt Entry Name: TBX18_HUMAN

NCBI Description

This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012]

Uniprot Description

TBX18: Probable transcriptional regulator involved in developmental processes.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 6q14-q15

Cellular Component: nucleus

Molecular Function: protein homodimerization activity; protein heterodimerization activity; transcription factor activity

Biological Process: somitogenesis; sensory perception of sound; morphogenesis of embryonic epithelium; transcription, DNA-dependent; positive regulation of cell-cell adhesion; smooth muscle cell differentiation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of epithelial cell proliferation; anterior/posterior axis specification

Disease: Huntington Disease