Rabbit anti-Human, Mouse TBPL1 Polyclonal Antibody | anti-TBPL1 antibody

TBPL1 Polyclonal Antibody

Cat. Num. AAA2562739

• Gene Names: TBPL1; TLF; TLP; STUD; TRF2; MGC:8389; MGC:9620
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: TBPL1; Polyclonal Antibody; TBPL1 Polyclonal Antibody; 21 kDa TBP-like protein; 21kDa TBP like protein; Second TBP of unique DNA; Second TBP of unique DNA protein; STUD; TATA box binding protein like protein 1; TATA box binding protein-related factor 2; TATA box-binding protein-like protein 1; TATA box-binding protein-related factor 2; TBP like 1; TBP like protein; TBP related factor 2; TBP-like factor; TBP-like protein 1; TBP-related factor 2; TBP-related protein; Tbpl1; TLF; TLP; TRF2; anti-TBPL1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 1.2mg/mL (varies by lot)
• Sequence Length: 186

• Applicable Applications for anti-TBPL1 antibody: Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:300; ELISA: 1:5000-1:10000
• Immunogen: Fusion protein of human TBPL1
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Mouse brain tissue lysate using TBPL1 Polyclonal Antibody at dilution of 1:400)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TBPL1 Polyclonal Antibody at dilution of 1:50(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TBPL1 Polyclonal Antibody at dilution of 1:50(×200))

Related Product Information for anti-TBPL1 antibody

This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.

Product Categories/Family for anti-TBPL1 antibody

Cancer; Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 358439409
• NCBI GeneID: 9519
• NCBI Accession #: NP_001240605.1; BC000381
• NCBI GenBank Nucleotide #: NP_001240605.1
• UniProt Accession #: P62380
• Molecular Weight: 21 kDa
• NCBI Official Full Name: TATA box-binding protein-like protein 1
• NCBI Official Synonym Full Names: TATA-box binding protein like 1
• NCBI Official Symbol: TBPL1
• NCBI Official Synonym Symbols: TLF; TLP; STUD; TRF2; MGC:8389; MGC:9620
• NCBI Protein Information: TATA box-binding protein-like protein 1
• UniProt Protein Name: TATA box-binding protein-like protein 1
• Protein Family: TATA box-binding protein-like protein
• UniProt Gene Name: TBPL1
• UniProt Synonym Gene Names: TLF; TLP; TLP21; TRF2; TRP; TBP-like protein 1; STUD; TBP-related factor 2
• UniProt Entry Name: TBPL1_HUMAN

NCBI Description

This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Nov 2011]

Uniprot Description

TBPL1: Does not bind the TATA box. Has DNA-binding ability. Belongs to the TBP family.

Protein type: Cell development/differentiation; DNA-binding; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: cytoplasm; transcription factor TFIIA complex

Molecular Function: DNA binding; transcription coactivator activity

Biological Process: acrosome formation; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription initiation; spermatid nuclear differentiation; dTTP biosynthetic process