Western Blot (WB)
(Western blot analysis of lysate from human heart tissue lysate, using TBCD7 Antibody (Center). MBS9205664 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Rabbit anti-Human TBCD7 Polyclonal Antibody | anti-TBC1D7 antibody
TBCD7 Antibody (Center)
Western Blot (WB)
(Western blot analysis of lysate from human heart tissue lysate, using TBCD7 Antibody (Center). MBS9205664 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of lysate from human heart tissue lysate, using TBCD7 Antibody (Center). MBS9205664 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Nakashima, A., et al. Biochem. Biophys. Res. Commun. 361(1):218-223(2007)
Larson, M.G., et al. BMC Med. Genet. 8 SUPPL 1, S5 (2007)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the TBC-domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1-TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
TBC1D7: a putative GTPase activating protein for Rab family protein(s).
Protein type: GAPs; GAPs, Rab
Chromosomal Location of Human Ortholog: 6p24.1
Cellular Component: cytoplasmic membrane-bound vesicle; cytoplasmic vesicle
Molecular Function: protein binding; Rab GTPase binding
Biological Process: negative regulation of TOR signaling pathway; positive regulation of protein ubiquitination
Disease: Macrocephaly/megalencephaly Syndrome, Autosomal Recessive
Research Articles on TBC1D7
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Product Notes
The TBC1D7 tbc1d7 (Catalog #AAA9205664) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 150-179. The TBCD7 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TBCD7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the TBC1D7 tbc1d7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TBCD7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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