Rabbit anti-Mouse Taok3 Polyclonal Antibody | anti-Taok3 antibody

Taok3, NT (Taok3, Serine/threonine-protein kinase TAO3, Thousand and one amino acid protein 3) (APC)

Cat. Num. AAA6353546

• Gene Names: Taok3; A130052D22; 2900006A08Rik; A430105I05Rik
• Reactivity: Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: Taok3; Polyclonal Antibody; NT (Taok3; Serine/threonine-protein kinase TAO3; Thousand and one amino acid protein 3) (APC); Thousand and one amino acid protein 3; anti-Taok3 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-Taok3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Mouse Taok3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-284 amino acids from the N-terminal region of Mouse Taok3.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Mouse Taok3 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Taok3 antibody detected the Taok3 protein (arrow).)

Related Product Information for anti-Taok3 antibody

Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK (By similarity).

Product Categories/Family for anti-Taok3 antibody

Antibodies; Protein Kinases

References

Stryke, D., et al. Nucleic Acids Res. 31(1):278-281(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 124486801
• NCBI GeneID: 330177
• NCBI Accession #: NP_001074777.1
• NCBI GenBank Nucleotide #: NM_001081308.2
• UniProt Accession #: Q8BYC6; Q3V3B3
• Molecular Weight: 105,336 Da
• NCBI Official Full Name: serine/threonine-protein kinase TAO3
• NCBI Official Synonym Full Names: TAO kinase 3
• NCBI Official Symbol: Taok3
• NCBI Official Synonym Symbols: A130052D22; 2900006A08Rik; A430105I05Rik
• NCBI Protein Information: serine/threonine-protein kinase TAO3; thousand and one amino acid protein 3
• UniProt Protein Name: Serine/threonine-protein kinase TAO3
• Protein Family: Serine/threonine-protein kinase
• UniProt Gene Name: Taok3

Uniprot Description

Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF) ().