Western Blot (WB)
(Western blot analysis of TALDO1 antibody (Center) in A375 cell line lysates (35ug/lane). TALDO1 (arrow) was detected using the purified Pab.)
Rabbit anti-Human TALDO1 Polyclonal Antibody | anti-TALDO1 antibody
TALDO1 Antibody (Center)
Western Blot (WB)
(Western blot analysis of TALDO1 antibody (Center) in A375 cell line lysates (35ug/lane). TALDO1 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of TALDO1 antibody (Center) in A375 cell line lysates (35ug/lane). TALDO1 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human lung carcinoma reacted with TALDO1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human lung carcinoma reacted with TALDO1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of K562 cells using TALDO1 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of K562 cells using TALDO1 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Western Blot (WB)
(Western blot analysis of TALDO1 (arrow) using rabbit polyclonal TALDO1 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TALDO1 gene.)
Western Blot (WB)
(Western blot analysis of TALDO1 (arrow) using rabbit polyclonal TALDO1 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TALDO1 gene.)
Qian,Y., Biochem. J. 415 (1), 123-134 (2008)
Wamelink,M.M., J. Inherit. Metab. Dis. 30 (5), 735-742 (2007)
NCBI and Uniprot Product Information
NCBI Description
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
Uniprot Description
TALDO1: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency). It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Belongs to the transaldolase family. Type 1 subfamily.
Protein type: EC 2.2.1.2; Transferase; Carbohydrate Metabolism - pentose phosphate pathway
Chromosomal Location of Human Ortholog: 11p15.5-p15.4
Cellular Component: cytoplasm; nucleus; cytosol
Molecular Function: transaldolase activity
Biological Process: pentose-phosphate shunt; carbohydrate metabolic process; energy reserve metabolic process; pathogenesis; xylulose biosynthetic process
Disease: Transaldolase Deficiency
Research Articles on TALDO1
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Product Notes
The TALDO1 taldo1 (Catalog #AAA9206259) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 186-215. The TALDO1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TALDO1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the TALDO1 taldo1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TALDO1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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