Rabbit anti-Human TALDO1 Polyclonal Antibody | anti-TALDO1 antibody

TALDO1 (Transaldolase, TALDOR, TALDO, TAL) (FITC)

Cat. Num. AAA6395986

• Gene Names: TALDO1; TAL; TALH; TAL-H; TALDOR
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TALDO1; Polyclonal Antibody; TALDO1 (Transaldolase; TALDOR; TALDO; TAL) (FITC); anti-TALDO1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human TALDO1.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-TALDO1 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human TALDO1, aa1-337 (NP_006746.1).
• Immunogen Sequence: MSSSPVKRQRMESALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGRKLGGSQEDQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPLEDPGVKSVTKIYNYYKKFSYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLQDNAKLVPVLSAKAAQASDLEKIHLDEKSFRWLHNEDQMAVEKLSDGIRKFAADAVKLERMLTERMFNAENGK
• Conjugate: FITC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TALDO1 rabbit polyclonal antibody. Western Blot analysis of TALDO1 expression in human pancreas.)

Western Blot (WB)

(TALDO1 rabbit polyclonal antibody. Western Blot analysis of TALDO1 expression in HepG2.)

Western Blot (WB)

(Western Blot analysis of TALDO1 expression in transfected 293T cell line by TALDO1 polyclonal antibody. Lane 1: TALDO1 transfected lysate (37.5kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-TALDO1 antibody

Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals.

Product Categories/Family for anti-TALDO1 antibody

Antibodies; Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 5803187
• NCBI GeneID: 6888
• NCBI Accession #: NP_006746.1
• NCBI GenBank Nucleotide #: NM_006755.1
• UniProt Accession #: P37837; O00751; Q8WV32; Q8WZ45; B2R8M2
• Molecular Weight: 37,540 Da
• NCBI Official Full Name: transaldolase
• NCBI Official Synonym Full Names: transaldolase 1
• NCBI Official Symbol: TALDO1
• NCBI Official Synonym Symbols: TAL; TALH; TAL-H; TALDOR
• NCBI Protein Information: transaldolase; dihydroxyacetone transferase; glycerone transferase
• UniProt Protein Name: Transaldolase
• Protein Family: Transaldolase
• UniProt Gene Name: TALDO1
• UniProt Synonym Gene Names: TAL; TALDO; TALDOR
• UniProt Entry Name: TALDO_HUMAN

NCBI Description

Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]

Uniprot Description

TALDO1: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency). It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Belongs to the transaldolase family. Type 1 subfamily.

Protein type: Carbohydrate Metabolism - pentose phosphate pathway; EC 2.2.1.2; Transferase

Chromosomal Location of Human Ortholog: 11p15.5-p15.4

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: transaldolase activity

Biological Process: pentose-phosphate shunt; carbohydrate metabolic process; energy reserve metabolic process; pathogenesis; xylulose biosynthetic process

Disease: Transaldolase Deficiency