Rabbit anti-Human SYT7 Polyclonal Antibody | anti-SYT7 antibody

SYT7 Polyclonal Antibody

Cat. Num. AAA9132588

• Gene Names: SYT7; IPCA7; IPCA-7; SYTVII; PCANAP7; SYT-VII
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purification
• Synonyms: SYT7; Polyclonal Antibody; SYT7 Polyclonal Antibody; IPCA-7; IPCA7; PCANAP7; SYT-VII; SYTVII; anti-SYT7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Sequence Length: 403

• Applicable Applications for anti-SYT7 antibody: Western Blot (WB)
• Application Notes: WB: 1:500 - 1:2000
• Immunogen: Recombinant protein of human SYT7
• Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using SYT7 antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 10s.)

Related Product Information for anti-SYT7 antibody

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Product Categories/Family for anti-SYT7 antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 206729907
• NCBI GeneID: 9066
• UniProt Accession #: O43581; Q08AH6; F5GZC2; F5GZU9; F5H126; F5H1N2; F5H6C1
• Molecular Weight: 46kDa
• NCBI Official Full Name: Synaptotagmin-7
• NCBI Official Synonym Full Names: synaptotagmin 7
• NCBI Official Symbol: SYT7
• NCBI Official Synonym Symbols: IPCA7; IPCA-7; SYTVII; PCANAP7; SYT-VII
• NCBI Protein Information: synaptotagmin-7
• UniProt Protein Name: Synaptotagmin-7
• Protein Family: Synaptotagmin
• UniProt Gene Name: SYT7
• UniProt Synonym Gene Names: SytVII

NCBI Description

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

SYT7: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: lysosome; peroxisome; plasma membrane; synaptic vesicle

Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; calmodulin binding; clathrin binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding; syntaxin binding

Biological Process: calcium ion-dependent exocytosis of neurotransmitter; phagocytosis; plasma membrane repair; regulation of bone remodeling; regulation of calcium ion-dependent exocytosis; regulation of insulin secretion; regulation of phagocytosis; vesicle fusion