Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (PSG2 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the PSG2 antibody detected the PSG2 protein (arrow).)

Rabbit anti-Human PSG2 Polyclonal Antibody | anti-PSG2 antibody

PSG2, CT (PSG2, PSBG2, Pregnancy-specific beta-1-glycoprotein 2, Pregnancy-specific beta-1 glycoprotein E) (AP)

Gene Names
PSG2; CEA; PSG1; PSBG2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PSG2; Polyclonal Antibody; CT (PSG2; PSBG2; Pregnancy-specific beta-1-glycoprotein 2; Pregnancy-specific beta-1 glycoprotein E) (AP); Pregnancy-specific beta-1 glycoprotein E; anti-PSG2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-PSG2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
PSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-254 amino acids from the C-terminal region of human PSG2.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(PSG2 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the PSG2 antibody detected the PSG2 protein (arrow).)

Western Blot (WB) (PSG2 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the PSG2 antibody detected the PSG2 protein (arrow).)
Related Product Information for anti-PSG2 antibody
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).
Product Categories/Family for anti-PSG2 antibody
References
Tsavaris, N., et al. J Chemother 21(6):673-680(2009). Mennuni, C., et al. Int. J. Cancer 117(3):444-455(2005). Colland, F., et al. Genome Res. 14(7):1324-1332(2004). Grimwood, J., et al. Nature 428(6982):529-535(2004). Teglund, S., et al. Genomics 23(3):669-684(1994).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,216 Da
NCBI Official Full Name
pregnancy-specific beta-1-glycoprotein 2
NCBI Official Synonym Full Names
pregnancy specific beta-1-glycoprotein 2
NCBI Official Symbol
PSG2
NCBI Official Synonym Symbols
CEA; PSG1; PSBG2
NCBI Protein Information
pregnancy-specific beta-1-glycoprotein 2
UniProt Protein Name
Pregnancy-specific beta-1-glycoprotein 2
UniProt Gene Name
PSG2
UniProt Synonym Gene Names
PSBG2; PS-beta-G-2; PSBG-2; Pregnancy-specific glycoprotein 2; PS-beta-E

NCBI Description

The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

Uniprot Description

PSG2: Belongs to the immunoglobulin superfamily. CEA family

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.31

Cellular Component: extracellular region

Biological Process: cell migration; female pregnancy

Research Articles on PSG2

Similar Products

Product Notes

The PSG2 psg2 (Catalog #AAA6338051) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PSG2, CT (PSG2, PSBG2, Pregnancy-specific beta-1-glycoprotein 2, Pregnancy-specific beta-1 glycoprotein E) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PSG2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PSG2 psg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.