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Goat Syt7 Polyclonal Antibody | anti-Syt7 antibody

Goat anti-Syt7 Antibody

Gene Names
SYT7; IPCA7; IPCA-7; SYTVII; PCANAP7; SYT-VII
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
Syt7; Polyclonal Antibody; Goat anti-Syt7 Antibody; synaptotagmin VII; AI851541; B230112P13Rik; synaptotagmin 7; AI851541 antibody; B230112P13Rik antibody; synaptotagmin 7 antibody; synaptotagmin VII antibody; Syt7 antibody; anti-Syt7 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
DIPTEKLRET
Sequence Length
403
Applicable Applications for anti-Syt7 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Preliminary experiments in Mouse and Rat Lung lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
Immunogen
Peptide with sequence C-DIPTEKLRET, from the internal region of the protein sequence according to NP_004191.2.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,700 Da
NCBI Official Full Name
synaptotagmin-7 isoform 2
NCBI Official Synonym Full Names
synaptotagmin 7
NCBI Official Symbol
SYT7
NCBI Official Synonym Symbols
IPCA7; IPCA-7; SYTVII; PCANAP7; SYT-VII
NCBI Protein Information
synaptotagmin-7
UniProt Protein Name
Synaptotagmin-7
Protein Family
UniProt Gene Name
SYT7
UniProt Synonym Gene Names
SytVII
UniProt Entry Name
SYT7_HUMAN

NCBI Description

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

SYT7: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: cell junction; cytosol; integral to membrane; lysosomal membrane; lysosome; peroxisomal membrane; peroxisome; phagocytic vesicle membrane; plasma membrane; presynaptic membrane; synaptic vesicle; synaptic vesicle membrane; terminal button

Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; calmodulin binding; clathrin binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding; syntaxin binding

Biological Process: calcium ion-dependent exocytosis of neurotransmitter; phagocytosis; plasma membrane repair; positive regulation of calcium ion-dependent exocytosis; regulation of bone remodeling; regulation of calcium ion-dependent exocytosis; regulation of insulin secretion; regulation of phagocytosis; vesicle fusion

Research Articles on Syt7

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Product Notes

The Syt7 syt7 (Catalog #AAA422648) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Syt7 Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's Syt7 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Preliminary experiments in Mouse and Rat Lung lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). Researchers should empirically determine the suitability of the Syt7 syt7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: DIPTEKLRET. It is sometimes possible for the material contained within the vial of "Syt7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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