Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SYT3 Polyclonal Antibody at dilution 1:50)
Rabbit SYT3 Polyclonal Antibody | anti-SYT3 antibody
SYT3 Polyclonal Antibody
Gene Names
SYT3; SytIII
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
SYT3; Polyclonal Antibody; SYT3 Polyclonal Antibody; SytIII; anti-SYT3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.1mg/mL (varies by lot)
Sequence Length
590
Applicable Applications for anti-SYT3 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Recombinant protein of human SYT3
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SYT3 Polyclonal Antibody at dilution 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SYT3 Polyclonal Antibody at dilution 1:50)
Related Product Information for anti-SYT3 antibody
Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
63,304 Da
NCBI Official Full Name
SYT3 protein
NCBI Official Synonym Full Names
synaptotagmin III
NCBI Official Symbol
SYT3
NCBI Official Synonym Symbols
SytIII
NCBI Protein Information
synaptotagmin-3
UniProt Protein Name
Synaptotagmin-3
Protein Family
UniProt Gene Name
SYT3
UniProt Synonym Gene Names
SytIII
UniProt Entry Name
SYT3_HUMAN
Uniprot Description
SYT3: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family.
Protein type: Calcium-binding; Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: synaptic vesicle membrane; integral to membrane; cell junction; endosome
Molecular Function: clathrin binding; syntaxin binding; calcium-dependent phospholipid binding; phosphatidylserine binding; transporter activity; metal ion binding
Biological Process: positive regulation of vesicle fusion; response to calcium ion; calcium ion-dependent exocytosis
Similar Products
Product Notes
The SYT3 syt3 (Catalog #AAA2519454) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYT3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SYT3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the SYT3 syt3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYT3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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