Western Blot (WB)
(Western Blot: Sample: Lane1: Human Liver Tissue; Lane2: Human 293T Cells; Lane3: Mouse Kidney Tissue.)
Rabbit anti-Human Syndecan 4 Polyclonal Antibody | anti-SDC4 antibody
Polyclonal Antibody to Syndecan 4 (SDC4)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-AES IRETEVIDPQ DLLEGRYFSG ALPDDEDVVG PGQESDDFEL SGSGDLDDLE DSMIGPEVVH PLVPLDNHIP ERAGSGSQVP TEPKKLEENE VIPKRISPVE ESEDVSNKVS MSSTVQGSNI FERTE
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Enzyme-linked Immunosorbent Assay: 0.05-2ug/mL
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Lane1: Human Liver Tissue; Lane2: Human 293T Cells; Lane3: Mouse Kidney Tissue.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Human Liver Tissue; Lane2: Human 293T Cells; Lane3: Mouse Kidney Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant SDC4, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant SDC4, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Human Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Human Tissue))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
Uniprot Description
syndecan-4: a heparan sulfate proteoglycan type I membrane protein that belongs to the syndecan proteoglycan family. Expressed as a homodimer. Promotes cell spreading in a beta(1) integrin-dependent fashion through PKC-alpha and Rho.
Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 20q13.12
Cellular Component: cell surface; costamere; extracellular exosome; focal adhesion; Golgi lumen; integral component of plasma membrane; lysosomal lumen; membrane raft; plasma membrane
Molecular Function: fibronectin binding; identical protein binding; protein binding; protein kinase C binding
Biological Process: cell migration; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; glycosaminoglycan metabolic process; inner ear receptor stereocilium organization and biogenesis; leukocyte migration; negative regulation of T cell proliferation; neural tube closure; positive regulation of focal adhesion assembly; positive regulation of protein kinase activity; positive regulation of stress fiber formation; regulation of fibroblast migration; retinoid metabolic process; signal transduction; ureteric bud development; wound healing
Research Articles on SDC4
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Product Notes
The SDC4 sdc4 (Catalog #AAA2025903) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Syndecan 4 (SDC4) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Syndecan 4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 1-5ug/mL Immunocytochemistry in formalin fixed cells: 5-20ug/mL Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL Immunohistochemistry in paraffin section: 5-20ug/mL Enzyme-linked Immunosorbent Assay: 0.05-2ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the SDC4 sdc4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-AES IRETEVIDPQ DLLEGRYFSG ALPDDEDVVG PGQESDDFEL SGSGDLDDLE DSMIGPEVVH PLVPLDNHIP ERAGSGSQVP TEPKKLEENE VIPKRISPVE ESEDVSNKVS MSSTVQGSNI FERTE. It is sometimes possible for the material contained within the vial of "Syndecan 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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