Rabbit SUPT6H Polyclonal Antibody | anti-SUPT6H antibody
SUPT6H Antibody (N-term)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Endoh, M., et al. Mol. Cell. Biol. 24(8):3324-3336(2004)
Wu-Baer, F., et al. J. Mol. Biol. 277(2):179-197(1998)
Chiang, P.W., et al. Genomics 47(3):426-428(1998)
NCBI and Uniprot Product Information
Uniprot Description
SPT6: promotes transcription elongation of many genes. A histone H3 chaperone that may alter chromatin structure during transcription. Binds RNA polymerase II (RNAPII) phosphorylated on Ser2 through its primitive SH2 domain, which appears to recognize phosphoserine rather than phosphotyrosine motifs. Associates with the nuclear mRNA export factor, THOC4.
Protein type: Nuclear receptor co-regulator; RNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: nucleus
Molecular Function: protein binding; DNA binding; histone binding; transcription factor activity
Biological Process: chromatin remodeling; regulation of isotype switching; regulation of muscle cell differentiation; mRNA transport; regulation of transcription, DNA-dependent; transcription, DNA-dependent; viral reproduction; positive regulation of RNA elongation from RNA polymerase II promoter; RNA splicing; mRNA processing; regulation of mRNA processing
Research Articles on SUPT6H
Similar Products
Product Notes
The SUPT6H supt6h (Catalog #AAA9214930) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 99-127. The SUPT6H Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's SUPT6H can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SUPT6H supt6h for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SUPT6H, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.