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Western Blot (WB) (SUPT6H Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SUPT6H antibody detected the SUPT6H protein (arrow).)

Rabbit SUPT6H Polyclonal Antibody | anti-SUPT6H antibody

SUPT6H Antibody (N-term)

Gene Names
SUPT6H; SPT6; SPT6H; emb-5
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SUPT6H; Polyclonal Antibody; SUPT6H Antibody (N-term); Transcription elongation factor SPT6; hSPT6; Histone chaperone suppressor of Ty6; Tat-cotransactivator 2 protein; Tat-CT2 protein; KIAA0162; SPT6H; anti-SUPT6H antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SUPT6H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-127 amino acids from the N-terminal region of human SUPT6H.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
99-127
Sequence Length
726
Applicable Applications for anti-SUPT6H antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(SUPT6H Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SUPT6H antibody detected the SUPT6H protein (arrow).)

Western Blot (WB) (SUPT6H Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SUPT6H antibody detected the SUPT6H protein (arrow).)
Related Product Information for anti-SUPT6H antibody
SUPT6H acts to stimulate transcriptional elongation by RNA polymerase II.
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Endoh, M., et al. Mol. Cell. Biol. 24(8):3324-3336(2004)
Wu-Baer, F., et al. J. Mol. Biol. 277(2):179-197(1998)
Chiang, P.W., et al. Genomics 47(3):426-428(1998)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
199073
NCBI Official Full Name
transcription elongation factor SPT6
NCBI Official Synonym Full Names
suppressor of Ty 6 homolog (S. cerevisiae)
NCBI Official Symbol
SUPT6H
NCBI Official Synonym Symbols
SPT6; SPT6H; emb-5
NCBI Protein Information
transcription elongation factor SPT6
UniProt Protein Name
Transcription elongation factor SPT6
UniProt Gene Name
SUPT6H
UniProt Synonym Gene Names
KIAA0162; SPT6H; hSPT6; Tat-CT2 protein
UniProt Entry Name
SPT6H_HUMAN

Uniprot Description

SPT6: promotes transcription elongation of many genes. A histone H3 chaperone that may alter chromatin structure during transcription. Binds RNA polymerase II (RNAPII) phosphorylated on Ser2 through its primitive SH2 domain, which appears to recognize phosphoserine rather than phosphotyrosine motifs. Associates with the nuclear mRNA export factor, THOC4.

Protein type: Nuclear receptor co-regulator; RNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: nucleus

Molecular Function: protein binding; DNA binding; histone binding; transcription factor activity

Biological Process: chromatin remodeling; regulation of isotype switching; regulation of muscle cell differentiation; mRNA transport; regulation of transcription, DNA-dependent; transcription, DNA-dependent; viral reproduction; positive regulation of RNA elongation from RNA polymerase II promoter; RNA splicing; mRNA processing; regulation of mRNA processing

Research Articles on SUPT6H

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Product Notes

The SUPT6H supt6h (Catalog #AAA9214930) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 99-127. The SUPT6H Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's SUPT6H can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SUPT6H supt6h for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SUPT6H, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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