SDS-Page
Suppressor Of Ty 6 Homolog Recombinant Protein | SUPT6H recombinant protein
Recombinant Suppressor Of Ty 6 Homolog (SUPT6H)
Gene Names
SUPT6H; SPT6; SPT6H; emb-5
Applications
SDS-Page, Western Blot, ELISA, Immunoprecipitation
Purity
>95%
Synonyms
Suppressor Of Ty 6 Homolog; Recombinant Suppressor Of Ty 6 Homolog (SUPT6H); SUPT6H recombinant protein
Host
Host: E Coli
Source: Prokaryotic expression
Source: Prokaryotic expression
Purity/Purification
>95%
Form/Format
Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Concentration
5.8 (varies by lot)
Sequence
The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-ESLFRE IRN DETGLWQCPF CQQDNFPELS EVWNHFDSGS CPGQAIGVKT RLDNGVTGFI PTKFLSDKVV KRPEERVKVG MTVHCRIMKI DIEKFSADLT CRTSDLMDRN NEWKLPKDTY YDFDAEAADH KQEEDM
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-ESLFRE IRN DETGLWQCPF CQQDNFPELS EVWNHFDSGS CPGQAIGVKT RLDNGVTGFI PTKFLSDKVV KRPEERVKVG MTVHCRIMKI DIEKFSADLT CRTSDLMDRN NEWKLPKDTY YDFDAEAADH KQEEDM
Sequence Length
1738
Applicable Applications for SUPT6H recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
Predicted Molecular Mass
19.5kDa
Accurate Molecular Mass (KD)
18kDa
Endotoxin
<1.0EU per 1ug (determined by the LAL method)
Expression System
Prokaryotic expression
Tag
two N-terminal Tags, His-tag and T7-tag
Organism Species
Homo sapiens (Human)
Fragment
ESLFRE
Usage
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
SDS-Page
SDS-Page
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
84,632 Da
NCBI Official Full Name
suppressor of Ty 6 homolog (S. cerevisiae), isoform CRA_c
NCBI Official Synonym Full Names
suppressor of Ty 6 homolog (S. cerevisiae)
NCBI Official Symbol
SUPT6H
NCBI Official Synonym Symbols
SPT6; SPT6H; emb-5
NCBI Protein Information
transcription elongation factor SPT6
UniProt Protein Name
Transcription elongation factor SPT6
Protein Family
UniProt Gene Name
SUPT6H
UniProt Synonym Gene Names
KIAA0162; SPT6H; hSPT6; Tat-CT2 protein
UniProt Entry Name
SPT6H_HUMAN
Uniprot Description
SPT6: promotes transcription elongation of many genes. A histone H3 chaperone that may alter chromatin structure during transcription. Binds RNA polymerase II (RNAPII) phosphorylated on Ser2 through its primitive SH2 domain, which appears to recognize phosphoserine rather than phosphotyrosine motifs. Associates with the nuclear mRNA export factor, THOC4.
Protein type: Nuclear receptor co-regulator; Transcription factor; RNA-binding
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: nucleus
Molecular Function: protein binding; DNA binding; histone binding; transcription factor activity
Biological Process: regulation of isotype switching; chromatin remodeling; regulation of muscle cell differentiation; mRNA transport; transcription, DNA-dependent; regulation of transcription, DNA-dependent; viral reproduction; positive regulation of RNA elongation from RNA polymerase II promoter; RNA splicing; mRNA processing; regulation of mRNA processing
Research Articles on SUPT6H
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Product Notes
The SUPT6H supt6h (Catalog #AAA2031501) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic expression and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Suppressor Of Ty 6 Homolog can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the SUPT6H supt6h for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.MGSSHHHHH H SSGLVPRGSH MASMTGGQQM GRGSEF-ESL FRE IRN DETGLWQCPF CQQDNFPELS EVWNHFDSGS CPGQAIGVKT RLDNGVTGFI PTKFLSDKVV KRPEERVKVG MTVHCRIMKI DIEKFSADLT CRTSDLMDRN NEWKLPKDTY YDFDAEAADH KQEEDM. It is sometimes possible for the material contained within the vial of "Suppressor Of Ty 6 Homolog, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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