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Western Blot (WB) (SUOX polyclonal antibody. Western Blot analysis of SUOX expression in human liver.)

Mouse anti-Human SUOX Polyclonal Antibody | anti-SUOX antibody

SUOX (Sulfite Oxidase, Mitochondrial)

Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
SUOX; Polyclonal Antibody; SUOX (Sulfite Oxidase; Mitochondrial); Anti -SUOX (Sulfite Oxidase; anti-SUOX antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human SUOX.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MGTLLGLGAVLAYQDHRCRAAQESTHIYTKEEVSSHTSPETGIWVTLGSEVFDVTEFVDLHPGGPSKLMLAAGGPLEPFWALYAVHNQSHVRELLAQYKIGELNPEDKVAPTVETSDPYADDPVRHPALKVNSQRPFNAEPPPELLTENYITPNPIFFTRNHLPVPNLDPDTYRLHVVGAPGGQSLSLSLDDLHNFPRYEITVTLQCAGNRRSEMTQVKEVKGLEWRTGAISTARWAGARLCDVLAQAGHQLCETEAHVCFEGLDSDPTGTAYGASIPLARAMDPEAEVLLAYEMNGQPLPRDHGFPVRVVVPGVVGARHVKWLGRVSVQPEESYSHWQRRDYKGFSPSVDWETVDFDSAPSIQELPVQSAITEPRDGETVESGEVTIKGYAWSGGGRAVIRVDVSLDGGLTWQVAKLDGEEQRPRKAWAWRLWQLKAPVPAGQKELNIVCKAVDDGYNVQPDTVAPIWNLRGVLSNAWHRVHVYVSP
Applicable Applications for anti-SUOX antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml
Immunogen
Full length human SUOX, aa1-488 (ENSP00000348440).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SUOX polyclonal antibody. Western Blot analysis of SUOX expression in human liver.)

Western Blot (WB) (SUOX polyclonal antibody. Western Blot analysis of SUOX expression in human liver.)

Western Blot (WB)

(SUOX polyclonal antibody. Western Blot analysis of SUOX expression in HepG2.)

Western Blot (WB) (SUOX polyclonal antibody. Western Blot analysis of SUOX expression in HepG2.)

Western Blot (WB)

(Western Blot analysis of SUOX expression in transfected 293T cell line by SUOX polyclonal antibody. Lane 1: SUOX transfected lysate (53.68kD). Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of SUOX expression in transfected 293T cell line by SUOX polyclonal antibody. Lane 1: SUOX transfected lysate (53.68kD). Lane 2: Non-transfected lysate.)

Immunohistochemistry (IHC)

(Immunoperoxidase of purified antibody to SUOX on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3ug/ml])

Immunohistochemistry (IHC) (Immunoperoxidase of purified antibody to SUOX on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3ug/ml])
Related Product Information for anti-SUOX antibody
Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.
Product Categories/Family for anti-SUOX antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60,283 Da
NCBI Official Full Name
sulfite oxidase, mitochondrial
NCBI Official Synonym Full Names
sulfite oxidase
NCBI Official Symbol
SUOX
NCBI Protein Information
sulfite oxidase, mitochondrial
UniProt Protein Name
Sulfite oxidase, mitochondrial
Protein Family
UniProt Gene Name
SUOX
UniProt Entry Name
SUOX_HUMAN

NCBI Description

Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq, Jul 2008]

Uniprot Description

SUOX: Defects in SUOX are the cause of isolated sulfite oxidase deficiency (ISOD); also known as sulfocysteinuria. ISOD is characterized by neurological abnormalities including multicystic leukoencephalopathy with brain atrophy. Patients often suffer from seizures. Often leads to death at an early age.

Protein type: Energy Metabolism - sulfur; EC 1.8.3.1; Oxidoreductase; Mitochondrial

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: mitochondrial matrix; mitochondrial intermembrane space

Molecular Function: molybdopterin cofactor binding; electron carrier activity; molybdenum ion binding; heme binding; sulfite oxidase activity

Biological Process: sulfur amino acid metabolic process; sulfur amino acid catabolic process

Disease: Sulfocysteinuria

Research Articles on SUOX

Similar Products

Product Notes

The SUOX suox (Catalog #AAA6006540) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SUOX (Sulfite Oxidase, Mitochondrial) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SUOX can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot and Immunohistochemistry. Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml. Researchers should empirically determine the suitability of the SUOX suox for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGTLLGLGAV LAYQDHRCRA AQESTHIYTK EEVSSHTSPE TGIWVTLGSE VFDVTEFVDL HPGGPSKLML AAGGPLEPFW ALYAVHNQSH VRELLAQYKI GELNPEDKVA PTVETSDPYA DDPVRHPALK VNSQRPFNAE PPPELLTENY ITPNPIFFTR NHLPVPNLDP DTYRLHVVGA PGGQSLSLSL DDLHNFPRYE ITVTLQCAGN RRSEMTQVKE VKGLEWRTGA ISTARWAGAR LCDVLAQAGH QLCETEAHVC FEGLDSDPTG TAYGASIPLA RAMDPEAEVL LAYEMNGQPL PRDHGFPVRV VVPGVVGARH VKWLGRVSVQ PEESYSHWQR RDYKGFSPSV DWETVDFDSA PSIQELPVQS AITEPRDGET VESGEVTIKG YAWSGGGRAV IRVDVSLDGG LTWQVAKLDG EEQRPRKAWA WRLWQLKAPV PAGQKELNIV CKAVDDGYNV QPDTVAPIWN LRGVLSNAWH RVHVYVSP. It is sometimes possible for the material contained within the vial of "SUOX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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