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Immunohistochemistry (IHC) (Immunochemical staining of human SULT1B1 in human spleen with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).)

Rabbit anti-Human SULT1B1 Polyclonal Antibody | anti-SULT1B1 antibody

Anti-SULT1B1 Antibody, Rabbit Polyclonal

Gene Names
SULT1B1; ST1B1; ST1B2; SULT1B2
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
SULT1B1; Polyclonal Antibody; Anti-SULT1B1 Antibody; Rabbit Polyclonal; SULT1B1 Antibody; Rabbit PAb; Antigen Affinity Purified; sulfotransferase family; cytosolic; 1B; member 1; Anti-ST1B1 Antibody; Anti-ST1B2 Antibody; Anti-SULT1B2 Antibody; anti-SULT1B1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human SULT1B1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-SULT1B1 antibody
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
ELISA: 1:5000-1:10,000
IHC-P: 1:500-1:2000
Immunogen
Recombinant Human SULT1B1 protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Human SULT1B1 (rh SULT1B1). SULT1B1 specific IgG was purified by Human SULT1B1 affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunochemical staining of human SULT1B1 in human spleen with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).)

Immunohistochemistry (IHC) (Immunochemical staining of human SULT1B1 in human spleen with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).)

Immunohistochemistry (IHC)

(Immunochemical staining of human SULT1B1 in human colon with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)

Immunohistochemistry (IHC) (Immunochemical staining of human SULT1B1 in human colon with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-SULT1B1 antibody
Sulfotransferase family cytosolic 1B member 1, also known as Sulfotransferase 1B1, Sulfotransferase 1B2, Thyroid hormone sulfotransferase, SULT1B1 and ST1B2, is a cytoplasm protein that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1B1 is highly expressed in the liver, peripheral blood leukocytes, colon (mucosal lining), small intestine (jejunum) and spleen. A lesser expression of SULT1B1 was observed in the lung, placenta and thymus. SULT1B1 catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. SULT1B1 sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3, 3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine.
References
Fujita K. et al., 1997, J. Biochem. 122:1052-61. Kester, MH.et al., 2003, Am J Physiol Endocrinol Metab. 285 (3):E592-8. Meinl W, et al., 2001, Biochem Biophys Res Commun. 288 (4): 855-62. Dombrovski L. et al., 2006, Proteins 64: 1091-4.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,899 Da
NCBI Official Full Name
sulfotransferase family cytosolic 1B member 1
NCBI Official Synonym Full Names
sulfotransferase family, cytosolic, 1B, member 1
NCBI Official Symbol
SULT1B1
NCBI Official Synonym Symbols
ST1B1; ST1B2; SULT1B2
NCBI Protein Information
sulfotransferase family cytosolic 1B member 1; sulfotransferase 1B1; sulfotransferase 1B2; thyroid hormone sulfotransferase
UniProt Protein Name
Sulfotransferase family cytosolic 1B member 1
UniProt Gene Name
SULT1B1
UniProt Synonym Gene Names
ST1B2; SULT1B2; ST1B1; Sulfotransferase 1B1; ST1B2
UniProt Entry Name
ST1B1_HUMAN

NCBI Description

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. [provided by RefSeq, Jul 2008]

Uniprot Description

SULT1B1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine. Belongs to the sulfotransferase 1 family.

Protein type: Transferase; EC 2.8.2.-

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: cytosol

Molecular Function: sulfotransferase activity; aryl sulfotransferase activity

Biological Process: steroid metabolic process; biogenic amine metabolic process; flavonoid metabolic process; epithelial cell differentiation; xenobiotic metabolic process; sulfation; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; thyroid hormone metabolic process; phenol metabolic process

Research Articles on SULT1B1

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Product Notes

The SULT1B1 sult1b1 (Catalog #AAA8105467) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SULT1B1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SULT1B1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:5000-1:10,000 IHC-P: 1:500-1:2000. Researchers should empirically determine the suitability of the SULT1B1 sult1b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SULT1B1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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