Rabbit anti-Human, Mouse STK17B Polyclonal Antibody | anti-STK17B antibody

STK17B Conjugated Antibody

Cat. Num. AAA9445971

• Gene Names: STK17B; DRAK2
• Reactivity: Human, Mouse
• Applications: Most Applications
• Synonyms: STK17B; Polyclonal Antibody; STK17B Conjugated Antibody; DAP kinase-related apoptosis-inducing protein kinase 2; DAP kinase-related apoptotic kinase 2; Death-associated protein kinase-related apoptosis inducing protein kinase; kinase DRAK2; Serine/threonine kinase 17B; anti-STK17B antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total STK17B protein.
• Form/Format: 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

• Applicable Applications for anti-STK17B antibody: Most Applications
• Application Notes: Suggested Dilution:; AF350 conjugated: most applications: 1:50-1:250; AF405 conjugated: most applications: 1:50-1:250; AF488 conjugated: most applications: 1:50-1:250; AF555 conjugated: most applications: 1:50-1:250; AF594 conjugated: most applications: 1:50-1:250; AF647 conjugated: most applications: 1:50-1:250; AF680 conjugated: most applications: 1:50-1:250; AF750 conjugated: most applications: 1:50-1:250; Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
• Immunogen: Synthesized peptide derived from internal of human STK17B.
• Conjugation: Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation Emission: AF350: 346nm/442nm
• Preparation and Storage: Store at 4 degree C for 6 months.

Related Product Information for anti-STK17B antibody

Phosphorylates myosin light chains by similarity. Acts as a positive regulator of apoptosis.

NCBI and Uniprot Product Information

• NCBI GI #: 4758194
• NCBI GeneID: 9262
• NCBI Accession #: NP_004217.1
• NCBI GenBank Nucleotide #: NM_004226.3
• UniProt Accession #: O94768
• Molecular Weight: 42,344 Da
• NCBI Official Full Name: serine/threonine-protein kinase 17B
• NCBI Official Synonym Full Names: serine/threonine kinase 17b
• NCBI Official Symbol: STK17B
• NCBI Official Synonym Symbols: DRAK2
• NCBI Protein Information: serine/threonine-protein kinase 17B; death-associated protein kinase-related 2; DAP kinase-related apoptosis-inducing protein kinase 2
• UniProt Protein Name: Serine/threonine-protein kinase 17B
• Protein Family: Serine/threonine-protein kinase
• UniProt Gene Name: STK17B
• UniProt Synonym Gene Names: DRAK2
• UniProt Entry Name: ST17B_HUMAN

Uniprot Description

DRAK2: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.

Protein type: Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; CAMK group; DAPK family

Chromosomal Location of Human Ortholog: 2q32.3

Cellular Component: plasma membrane; ER-Golgi intermediate compartment; nucleus; actin cytoskeleton

Molecular Function: protein serine/threonine kinase activity; ATP binding; protein kinase activity

Biological Process: apoptosis; protein amino acid autophosphorylation; protein amino acid phosphorylation