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Western Blot (WB) (Western BlotPositive WB detected in: HepG2 whole cell lysate,Mouse brain tissueAll lanes: STK17B antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 43 KDaObserved band size: 43 KDa)

Rabbit anti-Human STK17B Polyclonal Antibody | anti-STK17B antibody

STK17B Antibody

Gene Names
STK17B; DRAK2
Reactivity
Human
Applications
ELISA
Purity
>95%,Protein G purified
Synonyms
STK17B; Polyclonal Antibody; STK17B Antibody; Serine/threonine-protein kinase 17B; DAP kinase-related apoptosis-inducing protein kinase 2; DRAK2; anti-STK17B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
372
Applicable Applications for anti-STK17B antibody
ELISA (EIA)
Immunogen
Recombinant human Serine/threonine-protein kinase 17B protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9639 / sc-292771
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western BlotPositive WB detected in: HepG2 whole cell lysate,Mouse brain tissueAll lanes: STK17B antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 43 KDaObserved band size: 43 KDa)

Western Blot (WB) (Western BlotPositive WB detected in: HepG2 whole cell lysate,Mouse brain tissueAll lanes: STK17B antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 43 KDaObserved band size: 43 KDa)

Immunohistochemistry (IHC)

(IHC image of MBS7002529 diluted at 1:300 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 degree C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.)

Immunohistochemistry (IHC) (IHC image of MBS7002529 diluted at 1:300 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 degree C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.)
Related Product Information for anti-STK17B antibody
Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,344 Da
NCBI Official Full Name
serine/threonine-protein kinase 17B
NCBI Official Synonym Full Names
serine/threonine kinase 17b
NCBI Official Symbol
STK17B
NCBI Official Synonym Symbols
DRAK2
NCBI Protein Information
serine/threonine-protein kinase 17B
UniProt Protein Name
Serine/threonine-protein kinase 17B
UniProt Gene Name
STK17B
UniProt Synonym Gene Names
DRAK2
UniProt Entry Name
ST17B_HUMAN

Uniprot Description

DRAK2: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.

Protein type: EC 2.7.11.1; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CAMK group; DAPK family

Chromosomal Location of Human Ortholog: 2q32.3

Cellular Component: actin cytoskeleton; ER-Golgi intermediate compartment; nucleus; plasma membrane

Molecular Function: ATP binding; protein kinase activity; protein serine/threonine kinase activity

Biological Process: apoptosis; protein amino acid autophosphorylation; protein amino acid phosphorylation

Research Articles on STK17B

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Product Notes

The STK17B stk17b (Catalog #AAA7002529) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STK17B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STK17B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the STK17B stk17b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STK17B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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